Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes.
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| Title: | Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes. |
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| Authors: | Cai W; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Liu X; National Institute of Biological Science, Beijing, China., Barajas S; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Xiao S; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Vemula S; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Chen H; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; Department of Hematology and Oncology, Chongqing University Three Gorges Hospital, Chongqing, China., Yang Y; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; Department of Medical Genetics, School of Basic Medical Sciences, Peking University, Beijing, China., Bochers C; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Henley D; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Liu S; Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Jia Y; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Hong M; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Mays TM; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Capitano ML; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Liu H; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA., Ji P; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA.; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Gao Z; Department of Biochemistry and Molecular Biology, College of Medicine, Pennsylvania State University, Hershey, PA, 17033, USA., Pasini D; European Institute of Oncology IRCCS, Department of Experimental Oncology, Via Adamello 16, 20139, Milan, Italy.; University of Milan, Department of Health Sciences, Via A. di Rudinì 8, 20142, Milan, Italy., Wan J; Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Yue F; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Platanias LC; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA., Xi R; National Institute of Biological Science, Beijing, China., Chen S; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. sisichen@shsmu.edu.cn.; Precision Research Center for Refractory Diseases, Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China. sisichen@shsmu.edu.cn., Liu Y; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA. yan.liu@northwestern.edu.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. yan.liu@northwestern.edu.; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA. yan.liu@northwestern.edu. |
| Source: | Leukemia [Leukemia] 2025 Feb; Vol. 39 (2), pp. 296-307. Date of Electronic Publication: 2024 Nov 19. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39562720 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cai+W%22">Cai W</searchLink>; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; National Institute of Biological Science, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Barajas+S%22">Barajas S</searchLink>; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Xiao+S%22">Xiao S</searchLink>; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Vemula+S%22">Vemula S</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; Department of Hematology and Oncology, Chongqing University Three Gorges Hospital, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; Department of Medical Genetics, School of Basic Medical Sciences, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Bochers+C%22">Bochers C</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Henley+D%22">Henley D</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Jia+Y%22">Jia Y</searchLink>; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Hong+M%22">Hong M</searchLink>; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Mays+TM%22">Mays TM</searchLink>; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Capitano+ML%22">Capitano ML</searchLink>; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Ji+P%22">Ji P</searchLink>; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA.; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Gao+Z%22">Gao Z</searchLink>; Department of Biochemistry and Molecular Biology, College of Medicine, Pennsylvania State University, Hershey, PA, 17033, USA.<br /><searchLink fieldCode="AU" term="%22Pasini+D%22">Pasini D</searchLink>; European Institute of Oncology IRCCS, Department of Experimental Oncology, Via Adamello 16, 20139, Milan, Italy.; University of Milan, Department of Health Sciences, Via A. di Rudinì 8, 20142, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Wan+J%22">Wan J</searchLink>; Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Yue+F%22">Yue F</searchLink>; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Platanias+LC%22">Platanias LC</searchLink>; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Xi+R%22">Xi R</searchLink>; National Institute of Biological Science, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. sisichen@shsmu.edu.cn.; Precision Research Center for Refractory Diseases, Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China. sisichen@shsmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA. yan.liu@northwestern.edu.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. yan.liu@northwestern.edu.; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA. yan.liu@northwestern.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2025 Feb; Vol. 39 (2), pp. 296-307. <i>Date of Electronic Publication: </i>2024 Nov 19. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%2C+Specialist+Journals%22">Nature Publishing Group, Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8704895 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208876924%22">08876924 </searchLink><i>NLM ISO Abbreviation: </i>Leukemia <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39562720 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41375-024-02462-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 296 Titles: – TitleFull: Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cai W – PersonEntity: Name: NameFull: Liu X – PersonEntity: Name: NameFull: Barajas S – PersonEntity: Name: NameFull: Xiao S – PersonEntity: Name: NameFull: Vemula S – PersonEntity: Name: NameFull: Chen H – PersonEntity: Name: NameFull: Yang Y – PersonEntity: Name: NameFull: Bochers C – PersonEntity: Name: NameFull: Henley D – PersonEntity: Name: NameFull: Liu S – PersonEntity: Name: NameFull: Jia Y – PersonEntity: Name: NameFull: Hong M – PersonEntity: Name: NameFull: Mays TM – PersonEntity: Name: NameFull: Capitano ML – PersonEntity: Name: NameFull: Liu H – PersonEntity: Name: NameFull: Ji P – PersonEntity: Name: NameFull: Gao Z – PersonEntity: Name: NameFull: Pasini D – PersonEntity: Name: NameFull: Wan J – PersonEntity: Name: NameFull: Yue F – PersonEntity: Name: NameFull: Platanias LC – PersonEntity: Name: NameFull: Xi R – PersonEntity: Name: NameFull: Chen S – PersonEntity: Name: NameFull: Liu Y IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2025 Feb Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1476-5551 Numbering: – Type: volume Value: 39 – Type: issue Value: 2 Titles: – TitleFull: Leukemia Type: main |
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