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Plant-produced SARS-CoV-2 antibody engineered towards enhanced potency and in vivo efficacy.

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Title: Plant-produced SARS-CoV-2 antibody engineered towards enhanced potency and in vivo efficacy.
Authors: de Taeye SW; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands., Faye L; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France., Morel B; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France., Schriek AI; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands., Umotoy JC; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands., Yuan M; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA., Kuzmina NA; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.; Galveston National Laboratory, Galveston, Texas, USA., Turner HL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA., Zhu X; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA., Grünwald-Gruber C; BOKU Core Facility Mass Spectrometry, Universität für Bodenkultur Wien, Vienna, Austria., Poniman M; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands., Burger JA; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands., Caniels TG; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands., Fitchette AC; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France., Desgagnés R; ANGANY Inc, Québec, Quebec, Canada., Stordeur V; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France., Mirande L; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France., Beauverger G; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France., de Bree G; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands., Ozorowski G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA., Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA., Bukreyev A; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.; Galveston National Laboratory, Galveston, Texas, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA., Sanders RW; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, USA., Vezina LP; ANGANY Inc, Québec, Quebec, Canada., Beaumont T; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands., van Gils MJ; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands., Gomord V; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France.; ANGANY Inc, Québec, Quebec, Canada.
Source: Plant biotechnology journal [Plant Biotechnol J] 2025 Jan; Vol. 23 (1), pp. 4-16. Date of Electronic Publication: 2024 Nov 19.
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Society for Experimental Biology, Association of Applied Biologists Country of Publication: England NLM ID: 101201889 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-7652 (Electronic) Linking ISSN: 14677644 NLM ISO Abbreviation: Plant Biotechnol J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Plant-produced SARS-CoV-2 antibody engineered towards enhanced potency and in vivo efficacy.
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  Data: <searchLink fieldCode="AU" term="%22de+Taeye+SW%22">de Taeye SW</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Faye+L%22">Faye L</searchLink>; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France.<br /><searchLink fieldCode="AU" term="%22Morel+B%22">Morel B</searchLink>; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France.<br /><searchLink fieldCode="AU" term="%22Schriek+AI%22">Schriek AI</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Umotoy+JC%22">Umotoy JC</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Yuan+M%22">Yuan M</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Kuzmina+NA%22">Kuzmina NA</searchLink>; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.; Galveston National Laboratory, Galveston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Turner+HL%22">Turner HL</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Grünwald-Gruber+C%22">Grünwald-Gruber C</searchLink>; BOKU Core Facility Mass Spectrometry, Universität für Bodenkultur Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Poniman+M%22">Poniman M</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Burger+JA%22">Burger JA</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Caniels+TG%22">Caniels TG</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Fitchette+AC%22">Fitchette AC</searchLink>; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France.<br /><searchLink fieldCode="AU" term="%22Desgagnés+R%22">Desgagnés R</searchLink>; ANGANY Inc, Québec, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Stordeur+V%22">Stordeur V</searchLink>; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France.<br /><searchLink fieldCode="AU" term="%22Mirande+L%22">Mirande L</searchLink>; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France.<br /><searchLink fieldCode="AU" term="%22Beauverger+G%22">Beauverger G</searchLink>; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France.<br /><searchLink fieldCode="AU" term="%22de+Bree+G%22">de Bree G</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ozorowski+G%22">Ozorowski G</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+IA%22">Wilson IA</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Bukreyev+A%22">Bukreyev A</searchLink>; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.; Galveston National Laboratory, Galveston, Texas, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Sanders+RW%22">Sanders RW</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Vezina+LP%22">Vezina LP</searchLink>; ANGANY Inc, Québec, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Beaumont+T%22">Beaumont T</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Gils+MJ%22">van Gils MJ</searchLink>; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam institute for Immunology and Infectious Diseases, Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gomord+V%22">Gomord V</searchLink>; ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France.; ANGANY Inc, Québec, Quebec, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101201889%22">Plant biotechnology journal</searchLink> [Plant Biotechnol J] 2025 Jan; Vol. 23 (1), pp. 4-16. <i>Date of Electronic Publication: </i>2024 Nov 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+on+behalf+of+the+Society+for+Experimental+Biology%2C+Association+of+Applied+Biologists%22">Wiley on behalf of the Society for Experimental Biology, Association of Applied Biologists </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101201889 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1467-7652 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214677644%22">14677644 </searchLink><i>NLM ISO Abbreviation: </i>Plant Biotechnol J <i>Subsets: </i>MEDLINE
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