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Liver X receptor unlinks intestinal regeneration and tumorigenesis.

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Title: Liver X receptor unlinks intestinal regeneration and tumorigenesis.
Authors: Das S; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden. srustidhar.das@ki.se.; Center of Molecular Medicine, Stockholm, Sweden. srustidhar.das@ki.se., Parigi SM; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden.; Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY, USA., Luo X; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., Fransson J; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., Kern BC; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., Okhovat A; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden.; Structural Genomics Consortium, Division of Rheumatology, Department of Medicine Solna, Karolinska Institute and University Hospital, Stockholm, Sweden., Diaz OE; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., Sorini C; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., Czarnewski P; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden.; Science for Life Laboratory, Department of Biochemistry and Biophysics, National Bioinformatics Infrastructure Sweden, Stockholm University, Solna, Sweden., Webb AT; Department of Cell and Molecular Biology, Karolinska Institutet, Solna, Sweden., Morales RA; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., Lebon S; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Monasterio G; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., Castillo F; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., Tripathi KP; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., He N; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.; Center of Molecular Medicine, Stockholm, Sweden., Pelczar P; I. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Schaltenberg N; I. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., De la Fuente M; Center of Biomedical Research (CIBMED), School of Medicine, Faculty of Medicine-Clinica Las Condes, Universidad Finis Terrae, Santiago, Chile.; Laboratory of Innate Immunity, Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile., López-Köstner F; Centro de Enfermedades Digestivas, Programa Enfermedad Inflamatoria Intestinal, Clínica Universidad de Los Andes, Universidad de Los Andes, Santiago, Chile., Nylén S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Larsen HL; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), University of Copenhagen, Copenhagen, Denmark., Kuiper R; Section for Aquatic Biosecurity Research, Norwegian Veterinary Institute, Ås, Norway.; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden., Antonson P; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden., Hermoso MA; Laboratory of Innate Immunity, Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile., Huber S; I. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Biton M; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Scharaw S; Department of Cell and Molecular Biology, Karolinska Institutet, Solna, Sweden.; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany., Gustafsson JÅ; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.; Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX, USA., Katajisto P; Department of Cell and Molecular Biology, Karolinska Institutet, Solna, Sweden.; Institute of Biotechnology, University of Helsinki, Helsinki, Finland., Villablanca EJ; Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden. eduardo.villablanca@ki.se.; Center of Molecular Medicine, Stockholm, Sweden. eduardo.villablanca@ki.se.; Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden. eduardo.villablanca@ki.se.
Source: Nature [Nature] 2025 Jan; Vol. 637 (8048), pp. 1198-1206. Date of Electronic Publication: 2024 Nov 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: Liver X receptor unlinks intestinal regeneration and tumorigenesis.
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