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Single-cell integration reveals metaplasia in inflammatory gut diseases.

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Title: Single-cell integration reveals metaplasia in inflammatory gut diseases.
Authors: Oliver AJ; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Huang N; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Bartolome-Casado R; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Department of Pathology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, Norway., Li R; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, US., Koplev S; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Nilsen HR; Department of Pathology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, Norway., Moy M; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Cakir B; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Polanski K; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Gudiño V; Inflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain., Melón-Ardanaz E; Inflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain., Sumanaweera D; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Dimitrov D; Institute for Computational Biomedicine, Heidelberg University, Faculty of Medicine, Heidelberg University Hospital, Bioquant, Heidelberg, Germany., Milchsack LM; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., FitzPatrick MEB; Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Provine NM; Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Boccacino JM; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Dann E; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Predeus AV; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., To K; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Prete M; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Chapman JA; Translational and Clinical Research Institute, Newcastle University, Newcastle, UK., Masi AC; Translational and Clinical Research Institute, Newcastle University, Newcastle, UK., Stephenson E; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle, UK., Engelbert J; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle, UK., Lobentanzer S; Institute for Computational Biomedicine, Heidelberg University, Faculty of Medicine, Heidelberg University Hospital, Bioquant, Heidelberg, Germany., Perera S; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Richardson L; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Kapuge R; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Wilbrey-Clark A; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Semprich CI; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Ellams S; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Tudor C; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Joseph P; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Garrido-Trigo A; Inflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain., Corraliza AM; Inflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain., Oliver TRW; Department of Histopathology and Cytology, Cambridge University Hospitals, Cambridge, UK., Hook CE; Department of Pathology, University of Cambridge, Cambridge, UK., James KR; Translational Genomics, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.; School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia., Mahbubani KT; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge Biorepository for Translational Medicine, Cambridge NIHR Biomedical Research Centre, Cambridge, UK.; Department of Haematology, Cambridge Stem Cell Institute, Cambridge, UK., Saeb-Parsy K; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge Biorepository for Translational Medicine, Cambridge NIHR Biomedical Research Centre, Cambridge, UK., Zilbauer M; Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; University Department of Paediatrics, University of Cambridge, Cambridge, UK.; Department of Paediatric Gastroenterology, Hepatology and Nutrition, Cambridge University Hospitals, Cambridge, UK., Saez-Rodriguez J; Institute for Computational Biomedicine, Heidelberg University, Faculty of Medicine, Heidelberg University Hospital, Bioquant, Heidelberg, Germany., Høivik ML; Department of Gastroenterology, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Bækkevold ES; Department of Pathology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, Norway., Stewart CJ; Translational and Clinical Research Institute, Newcastle University, Newcastle, UK., Berrington JE; Translational and Clinical Research Institute, Newcastle University, Newcastle, UK., Meyer KB; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Klenerman P; Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Salas A; Inflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain., Haniffa M; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.; Department of Dermatology and National Institute for Health Research (NIHR) Newcastle Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Jahnsen FL; Department of Pathology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, Norway., Elmentaite R; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Ensocell Therapeutics, BioData Innovation Centre, Wellcome Genome Campus, Cambridge, UK., Teichmann SA; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. sat1003@cam.ac.uk.; Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. sat1003@cam.ac.uk.; Ensocell Therapeutics, BioData Innovation Centre, Wellcome Genome Campus, Cambridge, UK. sat1003@cam.ac.uk.; Theory of Condensed Matter, Cavendish Laboratory/Department of Physics, University of Cambridge, Cambridge, UK. sat1003@cam.ac.uk.; Department of Medicine, University of Cambridge, Cambridge, UK. sat1003@cam.ac.uk.; CIFAR Macmillan Multi-scale Human Program, CIFAR, Toronto, Ontario, Canada. sat1003@cam.ac.uk.
Source: Nature [Nature] 2024 Nov; Vol. 635 (8039), pp. 699-707. Date of Electronic Publication: 2024 Nov 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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DbLabel: MEDLINE Ultimate
An: 39567783
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Single-cell integration reveals metaplasia in inflammatory gut diseases.
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            NameFull: Høivik ML
      – PersonEntity:
          Name:
            NameFull: Bækkevold ES
      – PersonEntity:
          Name:
            NameFull: Stewart CJ
      – PersonEntity:
          Name:
            NameFull: Berrington JE
      – PersonEntity:
          Name:
            NameFull: Meyer KB
      – PersonEntity:
          Name:
            NameFull: Klenerman P
      – PersonEntity:
          Name:
            NameFull: Salas A
      – PersonEntity:
          Name:
            NameFull: Haniffa M
      – PersonEntity:
          Name:
            NameFull: Jahnsen FL
      – PersonEntity:
          Name:
            NameFull: Elmentaite R
      – PersonEntity:
          Name:
            NameFull: Teichmann SA
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 11
              Text: 2024 Nov
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 1476-4687
          Numbering:
            – Type: volume
              Value: 635
            – Type: issue
              Value: 8039
          Titles:
            – TitleFull: Nature
              Type: main
ResultId 1