Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.

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Title: Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.
Authors: Zheng SL; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Henry A; Institute of Cardiovascular Science, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK., Cannie D; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Lee M; National Heart and Lung Institute, Imperial College London, London, UK., Miller D; Division of Biosciences, University College London, London, UK., McGurk KA; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bond I; Institute of Cardiovascular Science, University College London, London, UK., Xu X; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Issa H; Institute of Health Informatics, University College London, London, UK., Francis C; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., De Marvao A; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Theotokis PI; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Buchan RJ; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Speed D; Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark., Abner E; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Adams L; Geisinger Health System, Danville, PA, USA., Aragam KG; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ärnlöv J; Department of Neurobiology, Care Sciences and Society/Section of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.; School of Health and Social Sciences, Dalarna University, Falun, Sweden., Raja AA; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Backman JD; Analytical Genetics, Regeneron Genetics Center, Tarrytown, NY, USA., Baksi J; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Barton PJR; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Biddinger KJ; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Boersma E; Erasmus MC, Cardiovascular Institute, Thorax Center, Department of Cardiology, Utrecht, the Netherlands., Brandimarto J; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Brunak S; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bundgaard H; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Carey DJ; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA., Charron P; Sorbonne Research Unit on Cardiovascular Disorders, Metabolism and Nutrition, Team Genomics & Pathophysiology of Cardiovascular Diseases, ICAN Institute for Cardiometabolism and Nutrition, Paris, France.; APHP, Department of Genetics, Pitié-Salpêtrière Hospital, Paris, France., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Cook SA; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Denaxas S; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK, University College London, London, UK.; British Heart Foundation Data Science Centre, London, UK.; The National Institute for Health Research University College London Hospitals Biomedical Research Centre, University College London, London, UK., Deleuze JF; Centre National de Recherche en Génomique Humaine (CNRGH), Institut de Biologie François Jacob, CEA, Université Paris-Saclay, Evry, France.; Laboratory of Excellence GENMED (Medical Genomics), Paris, France.; Centre d'Etude du Polymorphisme Humain, Fondation Jean Dausset, Paris, France., Doney AS; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Elliott P; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Erikstrup C; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.; Deparment of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Farber-Eger EH; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Finan C; Institute of Cardiovascular Science, University College London, London, UK., Garnier S; Sorbonne Research Unit on Cardiovascular Disorders, Metabolism and Nutrition, Team Genomics & Pathophysiology of Cardiovascular Diseases, ICAN Institute for Cardiometabolism and Nutrition, Paris, France., Ghouse J; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden., Guðbjartsson DF; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Haggerty CM; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA., Halliday BP; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Helgadottir A; deCODE genetics/Amgen Inc., Reykjavik, Iceland., Hemingway H; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK, University College London, London, UK., Hillege HL; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Kardys I; Erasmus MC, Cardiovascular Institute, Thorax Center, Department of Cardiology, Utrecht, the Netherlands., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Lindgren CM; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Lowery BD; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Manisty C; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Margulies KB; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Moon JC; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Mordi IR; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Morley MP; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Morris AD; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK., Morton L; Cardiovascular Research, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Noursadeghi M; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK., Ostrowski SR; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen University Hospital, Copenhagen, Denmark., Owens AT; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Palmer CNA; Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Pantazis A; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Pedersen OBV; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark., Prasad SK; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Shekhar A; Cardiovascular Research, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Smelser DT; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA., Srinivasan S; Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Stefansson K; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Medicine, University of Iceland, Reykjavik, Iceland., Sveinbjörnsson G; deCODE genetics/Amgen Inc., Reykjavik, Iceland., Syrris P; Institute of Cardiovascular Science, University College London, London, UK., Tammesoo ML; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Tayal U; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Teder-Laving M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Thorgeirsson G; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Medicine, University of Iceland, Reykjavik, Iceland., Thorsteinsdottir U; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Medicine, University of Iceland, Reykjavik, Iceland., Tragante V; deCODE genetics/Amgen Inc., Reykjavik, Iceland., Trégouët DA; Laboratory of Excellence GENMED (Medical Genomics), Paris, France.; Univ. Bordeaux, INSERM, BPH, Bordeaux, France., Treibel TA; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Ullum H; Statens Serum Institut, Copenhagen, Denmark., Valdes AM; Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham, UK., van Setten J; Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., van Vugt M; Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Veluchamy A; Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Verschuren WMM; Department Life Course, Lifestyle and Health, Centre for Prevention, Lifestyle and Health, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands., Villard E; Sorbonne Research Unit on Cardiovascular Disorders, Metabolism and Nutrition, Team Genomics & Pathophysiology of Cardiovascular Diseases, ICAN Institute for Cardiometabolism and Nutrition, Paris, France., Yang Y; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Asselbergs FW; Institute of Cardiovascular Science, University College London, London, UK.; The National Institute for Health Research University College London Hospitals Biomedical Research Centre, University College London, London, UK.; Department of Cardiology, Amsterdam University Medical Centers, Amsterdam, the Netherlands., Cappola TP; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Dube MP; Montreal Heart Institute, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Dunn ME; Cardiovascular Research, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Ellinor PT; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Hingorani AD; Institute of Cardiovascular Science, University College London, London, UK., Lang CC; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.; Tuanku Muhriz Chair, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia., Samani NJ; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Shah SH; Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC, USA.; Duke Clinical Research Institute, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA., Smith JG; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.; Department of Molecular and Clinical Medicine, Institute of Medicine, Gothenburg University and Sahlgrenska University Hospital, Gothenburg, Sweden.; Wallenberg Center for Molecular Medicine and Lund University Diabetes Center, Lund University, Lund, Sweden., Vasan RS; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Sections of Cardiology, Preventive Medicine and Epidemiology, Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, MA, USA., O'Regan DP; MRC Laboratory of Medical Sciences, London, UK., Holm H; deCODE genetics/Amgen Inc., Reykjavik, Iceland., Noseda M; National Heart and Lung Institute, Imperial College London, London, UK., Wells Q; Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN, USA., Ware JS; National Heart and Lung Institute, Imperial College London, London, UK. j.ware@imperial.ac.uk.; MRC Laboratory of Medical Sciences, London, UK. j.ware@imperial.ac.uk.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK. j.ware@imperial.ac.uk.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA. j.ware@imperial.ac.uk., Lumbers RT; Institute of Health Informatics, University College London, London, UK. t.lumbers@ucl.ac.uk.; Health Data Research UK, University College London, London, UK. t.lumbers@ucl.ac.uk.; British Heart Foundation Data Science Centre, London, UK. t.lumbers@ucl.ac.uk.
Corporate Authors: COVIDsortium, DBDS Genomic Consortium, Estonian Biobank Research Team, HERMES Consortium
Source: Nature genetics [Nat Genet] 2024 Dec; Vol. 56 (12), pp. 2646-2658. Date of Electronic Publication: 2024 Nov 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.
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  Label: Authors
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National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bond+I%22">Bond I</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Issa+H%22">Issa H</searchLink>; Institute of Health Informatics, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Francis+C%22">Francis C</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22De+Marvao+A%22">De Marvao A</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Theotokis+PI%22">Theotokis PI</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Buchan+RJ%22">Buchan RJ</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Speed+D%22">Speed D</searchLink>; Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Abner+E%22">Abner E</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Adams+L%22">Adams L</searchLink>; Geisinger Health System, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Aragam+KG%22">Aragam KG</searchLink>; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ärnlöv+J%22">Ärnlöv J</searchLink>; Department of Neurobiology, Care Sciences and Society/Section of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.; School of Health and Social Sciences, Dalarna University, Falun, Sweden.<br /><searchLink fieldCode="AU" term="%22Raja+AA%22">Raja AA</searchLink>; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Backman+JD%22">Backman JD</searchLink>; Analytical Genetics, Regeneron Genetics Center, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Baksi+J%22">Baksi J</searchLink>; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Barton+PJR%22">Barton PJR</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Biddinger+KJ%22">Biddinger KJ</searchLink>; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Boersma+E%22">Boersma E</searchLink>; Erasmus MC, Cardiovascular Institute, Thorax Center, Department of Cardiology, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Brandimarto+J%22">Brandimarto J</searchLink>; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Brunak+S%22">Brunak S</searchLink>; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Bundgaard+H%22">Bundgaard H</searchLink>; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Carey+DJ%22">Carey DJ</searchLink>; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Charron+P%22">Charron P</searchLink>; Sorbonne Research Unit on Cardiovascular Disorders, Metabolism and Nutrition, Team Genomics & Pathophysiology of Cardiovascular Diseases, ICAN Institute for Cardiometabolism and Nutrition, Paris, France.; APHP, Department of Genetics, Pitié-Salpêtrière Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cook+JP%22">Cook JP</searchLink>; Department of Biostatistics, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Cook+SA%22">Cook SA</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Denaxas+S%22">Denaxas S</searchLink>; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK, University College London, London, UK.; British Heart Foundation Data Science Centre, London, UK.; The National Institute for Health Research University College London Hospitals Biomedical Research Centre, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Deleuze+JF%22">Deleuze JF</searchLink>; Centre National de Recherche en Génomique Humaine (CNRGH), Institut de Biologie François Jacob, CEA, Université Paris-Saclay, Evry, France.; Laboratory of Excellence GENMED (Medical Genomics), Paris, France.; Centre d'Etude du Polymorphisme Humain, Fondation Jean Dausset, Paris, France.<br /><searchLink fieldCode="AU" term="%22Doney+AS%22">Doney AS</searchLink>; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Elliott+P%22">Elliott P</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Erikstrup+C%22">Erikstrup C</searchLink>; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.; Deparment of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Esko+T%22">Esko T</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Farber-Eger+EH%22">Farber-Eger EH</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Finan+C%22">Finan C</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Garnier+S%22">Garnier S</searchLink>; Sorbonne Research Unit on Cardiovascular Disorders, Metabolism and Nutrition, Team Genomics & Pathophysiology of Cardiovascular Diseases, ICAN Institute for Cardiometabolism and Nutrition, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ghouse+J%22">Ghouse J</searchLink>; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Giedraitis+V%22">Giedraitis V</searchLink>; Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Guðbjartsson+DF%22">Guðbjartsson DF</searchLink>; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Haggerty+CM%22">Haggerty CM</searchLink>; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Halliday+BP%22">Halliday BP</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Helgadottir+A%22">Helgadottir A</searchLink>; deCODE genetics/Amgen Inc., Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Hemingway+H%22">Hemingway H</searchLink>; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hillege+HL%22">Hillege HL</searchLink>; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kardys+I%22">Kardys I</searchLink>; Erasmus MC, Cardiovascular Institute, Thorax Center, Department of Cardiology, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Lind+L%22">Lind L</searchLink>; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Lindgren+CM%22">Lindgren CM</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lowery+BD%22">Lowery BD</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Manisty+C%22">Manisty C</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Margulies+KB%22">Margulies KB</searchLink>; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Moon+JC%22">Moon JC</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Mordi+IR%22">Mordi IR</searchLink>; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Morley+MP%22">Morley MP</searchLink>; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Morris+AD%22">Morris AD</searchLink>; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Morris+AP%22">Morris AP</searchLink>; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Morton+L%22">Morton L</searchLink>; Cardiovascular Research, Regeneron Pharmaceuticals, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Noursadeghi+M%22">Noursadeghi M</searchLink>; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ostrowski+SR%22">Ostrowski SR</searchLink>; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Owens+AT%22">Owens AT</searchLink>; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Palmer+CNA%22">Palmer CNA</searchLink>; Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Pantazis+A%22">Pantazis A</searchLink>; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Pedersen+OBV%22">Pedersen OBV</searchLink>; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark.<br /><searchLink fieldCode="AU" term="%22Prasad+SK%22">Prasad SK</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Shekhar+A%22">Shekhar A</searchLink>; Cardiovascular Research, Regeneron Pharmaceuticals, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Smelser+DT%22">Smelser DT</searchLink>; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Srinivasan+S%22">Srinivasan S</searchLink>; Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Stefansson+K%22">Stefansson K</searchLink>; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Sveinbjörnsson+G%22">Sveinbjörnsson G</searchLink>; deCODE genetics/Amgen Inc., Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Syrris+P%22">Syrris P</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Tammesoo+ML%22">Tammesoo ML</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Tayal+U%22">Tayal U</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Teder-Laving+M%22">Teder-Laving M</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Thorgeirsson+G%22">Thorgeirsson G</searchLink>; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Thorsteinsdottir+U%22">Thorsteinsdottir U</searchLink>; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Tragante+V%22">Tragante V</searchLink>; deCODE genetics/Amgen Inc., Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Trégouët+DA%22">Trégouët DA</searchLink>; Laboratory of Excellence GENMED (Medical Genomics), Paris, France.; Univ. Bordeaux, INSERM, BPH, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Treibel+TA%22">Treibel TA</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Ullum+H%22">Ullum H</searchLink>; Statens Serum Institut, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Valdes+AM%22">Valdes AM</searchLink>; Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22van+Setten+J%22">van Setten J</searchLink>; Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Vugt+M%22">van Vugt M</searchLink>; Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Veluchamy+A%22">Veluchamy A</searchLink>; Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Verschuren+WMM%22">Verschuren WMM</searchLink>; Department Life Course, Lifestyle and Health, Centre for Prevention, Lifestyle and Health, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Villard+E%22">Villard E</searchLink>; Sorbonne Research Unit on Cardiovascular Disorders, Metabolism and Nutrition, Team Genomics & Pathophysiology of Cardiovascular Diseases, ICAN Institute for Cardiometabolism and Nutrition, Paris, France.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Asselbergs+FW%22">Asselbergs FW</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.; The National Institute for Health Research University College London Hospitals Biomedical Research Centre, University College London, London, UK.; Department of Cardiology, Amsterdam University Medical Centers, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Cappola+TP%22">Cappola TP</searchLink>; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Dube+MP%22">Dube MP</searchLink>; Montreal Heart Institute, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Dunn+ME%22">Dunn ME</searchLink>; Cardiovascular Research, Regeneron Pharmaceuticals, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ellinor+PT%22">Ellinor PT</searchLink>; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hingorani+AD%22">Hingorani AD</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Lang+CC%22">Lang CC</searchLink>; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.; Tuanku Muhriz Chair, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Samani+NJ%22">Samani NJ</searchLink>; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Shah+SH%22">Shah SH</searchLink>; Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC, USA.; Duke Clinical Research Institute, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Smith+JG%22">Smith JG</searchLink>; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.; Department of Molecular and Clinical Medicine, Institute of Medicine, Gothenburg University and Sahlgrenska University Hospital, Gothenburg, Sweden.; Wallenberg Center for Molecular Medicine and Lund University Diabetes Center, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Vasan+RS%22">Vasan RS</searchLink>; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Sections of Cardiology, Preventive Medicine and Epidemiology, Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22O'Regan+DP%22">O'Regan DP</searchLink>; MRC Laboratory of Medical Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Holm+H%22">Holm H</searchLink>; deCODE genetics/Amgen Inc., Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Noseda+M%22">Noseda M</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Wells+Q%22">Wells Q</searchLink>; Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Ware+JS%22">Ware JS</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. j.ware@imperial.ac.uk.; MRC Laboratory of Medical Sciences, London, UK. j.ware@imperial.ac.uk.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK. j.ware@imperial.ac.uk.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA. j.ware@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Lumbers+RT%22">Lumbers RT</searchLink>; Institute of Health Informatics, University College London, London, UK. t.lumbers@ucl.ac.uk.; Health Data Research UK, University College London, London, UK. t.lumbers@ucl.ac.uk.; British Heart Foundation Data Science Centre, London, UK. t.lumbers@ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2024 Dec; Vol. 56 (12), pp. 2646-2658. <i>Date of Electronic Publication: </i>2024 Nov 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Co%22">Nature Pub. Co </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9216904 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-1718 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210614036%22">10614036 </searchLink><i>NLM ISO Abbreviation: </i>Nat Genet <i>Subsets: </i>MEDLINE
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      – TitleFull: Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.
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      – PersonEntity:
          Name:
            NameFull: Cappola TP
      – PersonEntity:
          Name:
            NameFull: Dube MP
      – PersonEntity:
          Name:
            NameFull: Dunn ME
      – PersonEntity:
          Name:
            NameFull: Ellinor PT
      – PersonEntity:
          Name:
            NameFull: Hingorani AD
      – PersonEntity:
          Name:
            NameFull: Lang CC
      – PersonEntity:
          Name:
            NameFull: Samani NJ
      – PersonEntity:
          Name:
            NameFull: Shah SH
      – PersonEntity:
          Name:
            NameFull: Smith JG
      – PersonEntity:
          Name:
            NameFull: Vasan RS
      – PersonEntity:
          Name:
            NameFull: O'Regan DP
      – PersonEntity:
          Name:
            NameFull: Holm H
      – PersonEntity:
          Name:
            NameFull: Noseda M
      – PersonEntity:
          Name:
            NameFull: Wells Q
      – PersonEntity:
          Name:
            NameFull: Ware JS
      – PersonEntity:
          Name:
            NameFull: Lumbers RT
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 12
              Text: 2024 Dec
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 1546-1718
          Numbering:
            – Type: volume
              Value: 56
            – Type: issue
              Value: 12
          Titles:
            – TitleFull: Nature genetics
              Type: main
ResultId 1