Exploring the therapeutic potential of precision T-Cell Receptors (TCRs) in targeting KRAS G12D cancer through in vitro development.

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Title: Exploring the therapeutic potential of precision T-Cell Receptors (TCRs) in targeting KRAS G12D cancer through in vitro development.
Authors: Zheng W; Sino-German Biomedical Center, National '111' Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Center of Industrial Fermentation (Ministry of Education of China & Hubei Province), Hubei University of Technology, Wuhan, 430068, China., Jiang D; Center of Research & Development, Beijing CorreGene Biotechnology Co., Ltd., Beijing, 102206, China., Chen S; Sino-German Biomedical Center, National '111' Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Center of Industrial Fermentation (Ministry of Education of China & Hubei Province), Hubei University of Technology, Wuhan, 430068, China., Wu M; Sino-German Biomedical Center, National '111' Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Center of Industrial Fermentation (Ministry of Education of China & Hubei Province), Hubei University of Technology, Wuhan, 430068, China., Yan B; Center of Research & Development, Beijing CorreGene Biotechnology Co., Ltd., Beijing, 102206, China., Zhai J; Center of Research & Development, Beijing CorreGene Biotechnology Co., Ltd., Beijing, 102206, China., Shi Y; Center of Research & Development, Beijing CorreGene Biotechnology Co., Ltd., Beijing, 102206, China., Xie B; Sino-German Biomedical Center, National '111' Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Center of Industrial Fermentation (Ministry of Education of China & Hubei Province), Hubei University of Technology, Wuhan, 430068, China., Xie X; Center of Research & Development, Beijing CorreGene Biotechnology Co., Ltd., Beijing, 102206, China., Hu K; Sino-German Biomedical Center, National '111' Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Center of Industrial Fermentation (Ministry of Education of China & Hubei Province), Hubei University of Technology, Wuhan, 430068, China., Ma W; Department of Medicine, Sanford Stem Cell Institute and Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
Source: Oncology research [Oncol Res] 2024 Nov 13; Vol. 32 (12), pp. 1837-1850. Date of Electronic Publication: 2024 Nov 13 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Tech Science Press Country of Publication: United States NLM ID: 9208097 Publication Model: eCollection Cited Medium: Internet ISSN: 1555-3906 (Electronic) Linking ISSN: 09650407 NLM ISO Abbreviation: Oncol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1555-3906
DOI:10.32604/or.2024.056565