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Post hoc analysis of ADAMANT, a phase 2 clinical trial of active tau immunotherapy with AADvac1 in patients with Alzheimer's disease, positive for plasma p-tau217.

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Title: Post hoc analysis of ADAMANT, a phase 2 clinical trial of active tau immunotherapy with AADvac1 in patients with Alzheimer's disease, positive for plasma p-tau217.
Authors: Kovacech B; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia. kovacech@axon-neuroscience.eu., Cullen NC; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Clinical Research Centre, Jan Waldenströms Gata 35, 202 13, Malmö, Sweden., Novak P; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia., Hanes J; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia., Kontsekova E; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102 Bratislava, Slovakia and Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska Cesta 9, Bratislava, 84510, Slovakia., Katina S; Department of Mathematics and Statistics, Axon Neuroscience R&D Services SE, Bratislava, Slovakia, and (current) Masaryk University, Kotlářská 267/2, Brno, 611 37, Czech Republic., Parrak V; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia., Fresser M; Axon Neuroscience SE, 4 Arch. Makariou & Kalogreon, 6016, Larnaca, Cyprus., Vanbrabant J; ADx NeuroSciences NV, Technologiepark 6, 9052, Ghent, Belgium., Feldman HH; Department of Neurosciences, Alzheimer's Disease Cooperative Study, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA., Winblad B; Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, BioClinicum, 171 64, Solna, Sweden.; Theme Inflammation and Aging, Karolinska University Hospital, 141 86, Stockholm, Sweden., Stoops E; ADx NeuroSciences NV, Technologiepark 6, 9052, Ghent, Belgium., Vanmechelen E; ADx NeuroSciences NV, Technologiepark 6, 9052, Ghent, Belgium., Zilka N; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia. zilka@axon-neuroscience.eu.
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Nov 23; Vol. 16 (1), pp. 254. Date of Electronic Publication: 2024 Nov 23.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Post hoc analysis of ADAMANT, a phase 2 clinical trial of active tau immunotherapy with AADvac1 in patients with Alzheimer's disease, positive for plasma p-tau217.
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  Data: <searchLink fieldCode="AU" term="%22Kovacech+B%22">Kovacech B</searchLink>; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia. kovacech@axon-neuroscience.eu.<br /><searchLink fieldCode="AU" term="%22Cullen+NC%22">Cullen NC</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Clinical Research Centre, Jan Waldenströms Gata 35, 202 13, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Novak+P%22">Novak P</searchLink>; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia.<br /><searchLink fieldCode="AU" term="%22Hanes+J%22">Hanes J</searchLink>; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia.<br /><searchLink fieldCode="AU" term="%22Kontsekova+E%22">Kontsekova E</searchLink>; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102 Bratislava, Slovakia and Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska Cesta 9, Bratislava, 84510, Slovakia.<br /><searchLink fieldCode="AU" term="%22Katina+S%22">Katina S</searchLink>; Department of Mathematics and Statistics, Axon Neuroscience R&D Services SE, Bratislava, Slovakia, and (current) Masaryk University, Kotlářská 267/2, Brno, 611 37, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Parrak+V%22">Parrak V</searchLink>; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia.<br /><searchLink fieldCode="AU" term="%22Fresser+M%22">Fresser M</searchLink>; Axon Neuroscience SE, 4 Arch. Makariou & Kalogreon, 6016, Larnaca, Cyprus.<br /><searchLink fieldCode="AU" term="%22Vanbrabant+J%22">Vanbrabant J</searchLink>; ADx NeuroSciences NV, Technologiepark 6, 9052, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Feldman+HH%22">Feldman HH</searchLink>; Department of Neurosciences, Alzheimer's Disease Cooperative Study, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.<br /><searchLink fieldCode="AU" term="%22Winblad+B%22">Winblad B</searchLink>; Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, BioClinicum, 171 64, Solna, Sweden.; Theme Inflammation and Aging, Karolinska University Hospital, 141 86, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Stoops+E%22">Stoops E</searchLink>; ADx NeuroSciences NV, Technologiepark 6, 9052, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Vanmechelen+E%22">Vanmechelen E</searchLink>; ADx NeuroSciences NV, Technologiepark 6, 9052, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Zilka+N%22">Zilka N</searchLink>; Axon Neuroscience R&D Services SE, Dvorakovo Nabr. 10, 81102, Bratislava, Slovakia. zilka@axon-neuroscience.eu.
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  Data: <searchLink fieldCode="JN" term="%22101511643%22">Alzheimer's research & therapy</searchLink> [Alzheimers Res Ther] 2024 Nov 23; Vol. 16 (1), pp. 254. <i>Date of Electronic Publication: </i>2024 Nov 23.
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  Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101511643 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1758-9193 (Electronic) <i>NLM ISO Abbreviation: </i>Alzheimers Res Ther <i>Subsets: </i>MEDLINE
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