BBSome-deficient cells activate intraciliary CDC42 to trigger actin-dependent ciliary ectocytosis.

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Title: BBSome-deficient cells activate intraciliary CDC42 to trigger actin-dependent ciliary ectocytosis.
Authors: Prasai A; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.; Faculty of Science, Department of Developmental and Cell Biology, Charles University, Prague, Czech Republic.; Center for Molecular Signaling (PZMS), Department of Medical Biochemistry and Molecular Biology, Saarland University School of Medicine, Homburg, Germany., Ivashchenko O; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.; Faculty of Science, Department of Developmental and Cell Biology, Charles University, Prague, Czech Republic., Maskova K; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Bykova S; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Schmidt Cernohorska M; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.; Max Perutz Labs, University of Vienna, Vienna Biocenter (VBC), Vienna, Austria., Stepanek O; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Huranova M; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic. martina.huranova@img.cas.cz.
Source: EMBO reports [EMBO Rep] 2025 Jan; Vol. 26 (1), pp. 36-60. Date of Electronic Publication: 2024 Nov 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-3178
DOI:10.1038/s44319-024-00326-z