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Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.

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Title: Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.
Authors: Topper MJ; COVID-19 International Research Team, Medford, MA 02155.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287., Guarnieri JW; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Haltom JA; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Chadburn A; Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065., Cope H; School of Medicine, University of Nottingham, Derby DE22 3DT, United Kingdom., Frere J; Icahn School of Medicine, Mount Sinai, New York, NY 10023., An J; COVID-19 International Research Team, Medford, MA 02155.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287., Borczuk A; Weill Cornell Medicine, New York, NY 10065., Sinha S; Weill Cornell Medicine, New York, NY 10065., Kim J; Weill Cornell Medicine, New York, NY 10065., Park J; Weill Cornell Medicine, New York, NY 10065., Butler D; Weill Cornell Medicine, New York, NY 10065., Meydan C; Weill Cornell Medicine, New York, NY 10065., Foox J; Weill Cornell Medicine, New York, NY 10065., Bram Y; Weill Cornell Medicine, New York, NY 10065., Richard SA; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817., Epsi NJ; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817., Agan B; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817., Chenoweth JG; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817., Simons MP; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814., Tribble D; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814., Burgess T; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814., Dalgard C; Department of Anatomy, Physiology & Genetics, Uniformed Services University, Bethesda, MD 20814., Heise MT; University of North Carolina, Chapel Hill, NC 27599., Moorman NJ; University of North Carolina, Chapel Hill, NC 27599., Baxter VK; University of North Carolina, Chapel Hill, NC 27599., Madden EA; University of North Carolina, Chapel Hill, NC 27599., Taft-Benz SA; University of North Carolina, Chapel Hill, NC 27599., Anderson EJ; University of North Carolina, Chapel Hill, NC 27599., Sanders WA; University of North Carolina, Chapel Hill, NC 27599., Dickmander RJ; University of North Carolina, Chapel Hill, NC 27599., Beigel K; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Biomedical and Health, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Widjaja GA; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Janssen KA; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Lie T; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Murdock DG; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Angelin A; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Soto Albrecht YE; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; The University of Pennsylvania, Philadelphia, PA 19104., Olali AZ; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Cen Z; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Dybas J; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104., Priebe W; COVID-19 International Research Team, Medford, MA 02155.; University of Texas Monroe Dunaway Anderson Cancer Center, Houston, TX 77030., Emmett MR; COVID-19 International Research Team, Medford, MA 02155.; University of Texas Medical Branch, Galveston, TX 77555., Best SM; COVID-19 International Research Team, Medford, MA 02155.; Innate Immunity and Pathogenesis Section, Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, NIH, Rocky Mountain Laboratories, Hamilton, MT 59840., Kelsey Johnson M; COVID-19 International Research Team, Medford, MA 02155.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287., Trovao NS; COVID-19 International Research Team, Medford, MA 02155.; Fogarty International Center, NIH, Bethesda, MD 20892., Clark KB; COVID-19 International Research Team, Medford, MA 02155.; Cures Within Reach, Chicago, IL 60602.; Champions Service, Computational Sciences Support Network, Multi-Tier Assistance, Training, and Computational Help Track, NSF's Advanced Cyberinfrastructure Coordination Ecosystem: Services and Support, Carnegie-Mellon University, Pittsburgh, PA 15213., Zaksas V; COVID-19 International Research Team, Medford, MA 02155.; Center for Translational Data Science, University of Chicago, Chicago, IL 60615.; Clever Research Lab, Springfield, IL 62704., Meller R; COVID-19 International Research Team, Medford, MA 02155.; Morehouse School of Medicine, Atlanta, GA 30310., Grabham P; COVID-19 International Research Team, Medford, MA 02155.; Center for Radiological Research, College of Physicians and Surgeons, Columbia University, New York, NY 19103., Schisler JC; COVID-19 International Research Team, Medford, MA 02155.; University of North Carolina, Chapel Hill, NC 27599., Moraes-Vieira PM; COVID-19 International Research Team, Medford, MA 02155.; Laboratory of Immunometabolism, Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, São Paulo, Brazil 13083-862., Pollett S; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817., Mason CE; COVID-19 International Research Team, Medford, MA 02155.; Weill Cornell Medicine, New York, NY 10065.; New York Genome Center, New York, NY 10013., Syrkin Wurtele E; COVID-19 International Research Team, Medford, MA 02155.; Center for Metabolic Biology, Bioinformatics and Computational Biology, and Genetics Development, and Cell Biology, Iowa State University, Ames, IA 50011.; Center for Bioinformatics and Computational Biology Iowa State University, Ames, IA 50011.; Center for Genetics Development, and Cell Biology Iowa State University, Ames, IA 50011., Taylor D; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Biomedical and Health, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104., Schwartz RE; COVID-19 International Research Team, Medford, MA 02155.; Weill Cornell Medicine, New York, NY 10065., Beheshti A; COVID-19 International Research Team, Medford, MA 02155.; Stanley Center for Psychiatric Research, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142.; Blue Marble Space Institute of Science, Seattle, WA 98104.; McGowan Institute for Regenerative Medicine and Center for Space Biomedicine, Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15219., Wallace DC; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Division of Human Genetics, Department of Pediatrics, University of Pennsylvania, Philadelphia, PA 19104., Baylin SB; COVID-19 International Research Team, Medford, MA 02155.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287.; Van Andel Institute, Grand Rapids, MI 49503.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Dec 03; Vol. 121 (49), pp. e2401968121. Date of Electronic Publication: 2024 Nov 27.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.
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  Data: <searchLink fieldCode="AU" term="%22Topper+MJ%22">Topper MJ</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287.<br /><searchLink fieldCode="AU" term="%22Guarnieri+JW%22">Guarnieri JW</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Haltom+JA%22">Haltom JA</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Chadburn+A%22">Chadburn A</searchLink>; Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Cope+H%22">Cope H</searchLink>; School of Medicine, University of Nottingham, Derby DE22 3DT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Frere+J%22">Frere J</searchLink>; Icahn School of Medicine, Mount Sinai, New York, NY 10023.<br /><searchLink fieldCode="AU" term="%22An+J%22">An J</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287.<br /><searchLink fieldCode="AU" term="%22Borczuk+A%22">Borczuk A</searchLink>; Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Sinha+S%22">Sinha S</searchLink>; Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Butler+D%22">Butler D</searchLink>; Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Meydan+C%22">Meydan C</searchLink>; Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Foox+J%22">Foox J</searchLink>; Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Bram+Y%22">Bram Y</searchLink>; Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Richard+SA%22">Richard SA</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817.<br /><searchLink fieldCode="AU" term="%22Epsi+NJ%22">Epsi NJ</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817.<br /><searchLink fieldCode="AU" term="%22Agan+B%22">Agan B</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817.<br /><searchLink fieldCode="AU" term="%22Chenoweth+JG%22">Chenoweth JG</searchLink>; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817.<br /><searchLink fieldCode="AU" term="%22Simons+MP%22">Simons MP</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.<br /><searchLink fieldCode="AU" term="%22Tribble+D%22">Tribble D</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.<br /><searchLink fieldCode="AU" term="%22Burgess+T%22">Burgess T</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.<br /><searchLink fieldCode="AU" term="%22Dalgard+C%22">Dalgard C</searchLink>; Department of Anatomy, Physiology & Genetics, Uniformed Services University, Bethesda, MD 20814.<br /><searchLink fieldCode="AU" term="%22Heise+MT%22">Heise MT</searchLink>; University of North Carolina, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Moorman+NJ%22">Moorman NJ</searchLink>; University of North Carolina, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Baxter+VK%22">Baxter VK</searchLink>; University of North Carolina, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Madden+EA%22">Madden EA</searchLink>; University of North Carolina, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Taft-Benz+SA%22">Taft-Benz SA</searchLink>; University of North Carolina, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Anderson+EJ%22">Anderson EJ</searchLink>; University of North Carolina, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Sanders+WA%22">Sanders WA</searchLink>; University of North Carolina, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Dickmander+RJ%22">Dickmander RJ</searchLink>; University of North Carolina, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Beigel+K%22">Beigel K</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Biomedical and Health, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Widjaja+GA%22">Widjaja GA</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Janssen+KA%22">Janssen KA</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Lie+T%22">Lie T</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Murdock+DG%22">Murdock DG</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Angelin+A%22">Angelin A</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Soto+Albrecht+YE%22">Soto Albrecht YE</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; The University of Pennsylvania, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Olali+AZ%22">Olali AZ</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Cen+Z%22">Cen Z</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Dybas+J%22">Dybas J</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Priebe+W%22">Priebe W</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; University of Texas Monroe Dunaway Anderson Cancer Center, Houston, TX 77030.<br /><searchLink fieldCode="AU" term="%22Emmett+MR%22">Emmett MR</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; University of Texas Medical Branch, Galveston, TX 77555.<br /><searchLink fieldCode="AU" term="%22Best+SM%22">Best SM</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Innate Immunity and Pathogenesis Section, Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, NIH, Rocky Mountain Laboratories, Hamilton, MT 59840.<br /><searchLink fieldCode="AU" term="%22Kelsey+Johnson+M%22">Kelsey Johnson M</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287.<br /><searchLink fieldCode="AU" term="%22Trovao+NS%22">Trovao NS</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Fogarty International Center, NIH, Bethesda, MD 20892.<br /><searchLink fieldCode="AU" term="%22Clark+KB%22">Clark KB</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Cures Within Reach, Chicago, IL 60602.; Champions Service, Computational Sciences Support Network, Multi-Tier Assistance, Training, and Computational Help Track, NSF's Advanced Cyberinfrastructure Coordination Ecosystem: Services and Support, Carnegie-Mellon University, Pittsburgh, PA 15213.<br /><searchLink fieldCode="AU" term="%22Zaksas+V%22">Zaksas V</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Center for Translational Data Science, University of Chicago, Chicago, IL 60615.; Clever Research Lab, Springfield, IL 62704.<br /><searchLink fieldCode="AU" term="%22Meller+R%22">Meller R</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Morehouse School of Medicine, Atlanta, GA 30310.<br /><searchLink fieldCode="AU" term="%22Grabham+P%22">Grabham P</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Center for Radiological Research, College of Physicians and Surgeons, Columbia University, New York, NY 19103.<br /><searchLink fieldCode="AU" term="%22Schisler+JC%22">Schisler JC</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; University of North Carolina, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Moraes-Vieira+PM%22">Moraes-Vieira PM</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Laboratory of Immunometabolism, Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, São Paulo, Brazil 13083-862.<br /><searchLink fieldCode="AU" term="%22Pollett+S%22">Pollett S</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817.<br /><searchLink fieldCode="AU" term="%22Mason+CE%22">Mason CE</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Weill Cornell Medicine, New York, NY 10065.; New York Genome Center, New York, NY 10013.<br /><searchLink fieldCode="AU" term="%22Syrkin+Wurtele+E%22">Syrkin Wurtele E</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Center for Metabolic Biology, Bioinformatics and Computational Biology, and Genetics Development, and Cell Biology, Iowa State University, Ames, IA 50011.; Center for Bioinformatics and Computational Biology Iowa State University, Ames, IA 50011.; Center for Genetics Development, and Cell Biology Iowa State University, Ames, IA 50011.<br /><searchLink fieldCode="AU" term="%22Taylor+D%22">Taylor D</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Biomedical and Health, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Schwartz+RE%22">Schwartz RE</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Weill Cornell Medicine, New York, NY 10065.<br /><searchLink fieldCode="AU" term="%22Beheshti+A%22">Beheshti A</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Stanley Center for Psychiatric Research, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142.; Blue Marble Space Institute of Science, Seattle, WA 98104.; McGowan Institute for Regenerative Medicine and Center for Space Biomedicine, Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15219.<br /><searchLink fieldCode="AU" term="%22Wallace+DC%22">Wallace DC</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Division of Human Genetics, Department of Pediatrics, University of Pennsylvania, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Baylin+SB%22">Baylin SB</searchLink>; COVID-19 International Research Team, Medford, MA 02155.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287.; Van Andel Institute, Grand Rapids, MI 49503.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2024 Dec 03; Vol. 121 (49), pp. e2401968121. <i>Date of Electronic Publication: </i>2024 Nov 27.
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          Dates:
            – D: 03
              M: 12
              Text: 2024 Dec 03
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 1091-6490
          Numbering:
            – Type: volume
              Value: 121
            – Type: issue
              Value: 49
          Titles:
            – TitleFull: Proceedings of the National Academy of Sciences of the United States of America
              Type: main
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