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The Ercc1-/Δ mouse model of XFE progeroid syndrome undergoes accelerated retinal degeneration.

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Title: The Ercc1-/Δ mouse model of XFE progeroid syndrome undergoes accelerated retinal degeneration.
Authors: Narasimhan A; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Min SH; Department of Ophthalmology, University of Florida, Gainesville, Florida, USA., Johnson LL; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA., Roehrich H; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA., Cho W; Department of Physiology and Biophysics, Department of Ophthalmology, Center for Translational Vision Research, University of California Irvine, School of Medicine, Irvine, California, USA., Her TK; Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, Minnesota, USA., Windschitl C; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., O'Kelly RD; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Angelini L; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Yousefzadeh MJ; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., McLoon LK; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA., Hauswirth WW; Department of Ophthalmology, University of Florida, Gainesville, Florida, USA., Robbins PD; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Skowronska-Krawczyk D; Department of Physiology and Biophysics, Department of Ophthalmology, Center for Translational Vision Research, University of California Irvine, School of Medicine, Irvine, California, USA., Niedernhofer LJ; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
Source: Aging cell [Aging Cell] 2025 Mar; Vol. 24 (3), pp. e14419. Date of Electronic Publication: 2024 Nov 27.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The Ercc1<superscript>-/Δ</superscript> mouse model of XFE progeroid syndrome undergoes accelerated retinal degeneration.
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  Data: <searchLink fieldCode="AU" term="%22Narasimhan+A%22">Narasimhan A</searchLink>; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Min+SH%22">Min SH</searchLink>; Department of Ophthalmology, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+LL%22">Johnson LL</searchLink>; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Roehrich+H%22">Roehrich H</searchLink>; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Cho+W%22">Cho W</searchLink>; Department of Physiology and Biophysics, Department of Ophthalmology, Center for Translational Vision Research, University of California Irvine, School of Medicine, Irvine, California, USA.<br /><searchLink fieldCode="AU" term="%22Her+TK%22">Her TK</searchLink>; Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Windschitl+C%22">Windschitl C</searchLink>; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22O'Kelly+RD%22">O'Kelly RD</searchLink>; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Angelini+L%22">Angelini L</searchLink>; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Yousefzadeh+MJ%22">Yousefzadeh MJ</searchLink>; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22McLoon+LK%22">McLoon LK</searchLink>; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Hauswirth+WW%22">Hauswirth WW</searchLink>; Department of Ophthalmology, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Robbins+PD%22">Robbins PD</searchLink>; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Skowronska-Krawczyk+D%22">Skowronska-Krawczyk D</searchLink>; Department of Physiology and Biophysics, Department of Ophthalmology, Center for Translational Vision Research, University of California Irvine, School of Medicine, Irvine, California, USA.<br /><searchLink fieldCode="AU" term="%22Niedernhofer+LJ%22">Niedernhofer LJ</searchLink>; Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
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  Data: <searchLink fieldCode="JN" term="%22101130839%22">Aging cell</searchLink> [Aging Cell] 2025 Mar; Vol. 24 (3), pp. e14419. <i>Date of Electronic Publication: </i>2024 Nov 27.
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