De novo variants in LRRC8C resulting in constitutive channel activation cause a human multisystem disorder. - Quinodoz M; Rutz S; Peter V; Garavelli L; Innes AM; Lehmann EF; Kellenberger S; Peng Z; Barone A; Campos-Xavier B; Unger S; Rivolta C; et al. (The EMBO journal, 2025)