Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases.
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| Title: | Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases. |
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| Authors: | Tian C; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore., Zhang Y; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tong Y; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore., Kock KH; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Sim DY; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Liu F; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore., Dong J; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Jing Z; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Wang W; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore.; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Gao J; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore., Tan LM; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Han KY; Samsung Genome Institute, Samsung Medical Center, Seoul, South Korea., Tomofuji Y; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Nakano M; Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan., Buyamin EV; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Sonthalia R; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ando Y; Laboratory for Advanced Genomics Circuit, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan., Hatano H; Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan., Sonehara K; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Jin X; BGI Research, Shenzhen, China.; The Innovation Centre of Ministry of Education for Development and Diseases, School of Medicine, South China University of Technology, Guangzhou, China.; Shanxi Medical University-BGI Collaborative Center for Future Medicine, Shanxi Medical University, Taiyuan, China.; Shenzhen Key Laboratory of Transomics Biotechnologies, BGI Research, Shenzhen, China., Loh M; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Chambers J; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Hon CC; Laboratory for Genome Information Analysis, RIKEN Center for Integrative Medical Sciences, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Japan., Choi M; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea., Park JE; Graduate School of Medical Science and Engineering, KAIST, Daejeon, South Korea., Ishigaki K; Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan., Okamura T; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Fujio K; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Okada Y; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan.; Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), Osaka University, Suita, Japan., Park WY; Samsung Genome Institute, Samsung Medical Center, Seoul, South Korea., Shin JW; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Laboratory for Advanced Genomics Circuit, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Roca X; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Prabhakar S; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Liu B; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg.; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg.; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. boxiangliu@nus.edu.sg.; Precision Medicine Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg.; Cardiovascular-Metabolic Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg. |
| Corporate Authors: | Asian Immune Diversity Atlas Network |
| Source: | Nature genetics [Nat Genet] 2024 Dec; Vol. 56 (12), pp. 2739-2752. Date of Electronic Publication: 2024 Dec 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39627432 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tian+C%22">Tian C</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tong+Y%22">Tong Y</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kock+KH%22">Kock KH</searchLink>; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Sim+DY%22">Sim DY</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+F%22">Liu F</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Dong+J%22">Dong J</searchLink>; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Jing+Z%22">Jing Z</searchLink>; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore.; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Gao+J%22">Gao J</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+LM%22">Tan LM</searchLink>; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Han+KY%22">Han KY</searchLink>; Samsung Genome Institute, Samsung Medical Center, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Tomofuji+Y%22">Tomofuji Y</searchLink>; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Nakano+M%22">Nakano M</searchLink>; Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.<br /><searchLink fieldCode="AU" term="%22Buyamin+EV%22">Buyamin EV</searchLink>; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Sonthalia+R%22">Sonthalia R</searchLink>; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ando+Y%22">Ando Y</searchLink>; Laboratory for Advanced Genomics Circuit, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.<br /><searchLink fieldCode="AU" term="%22Hatano+H%22">Hatano H</searchLink>; Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.<br /><searchLink fieldCode="AU" term="%22Sonehara+K%22">Sonehara K</searchLink>; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Jin+X%22">Jin X</searchLink>; BGI Research, Shenzhen, China.; The Innovation Centre of Ministry of Education for Development and Diseases, School of Medicine, South China University of Technology, Guangzhou, China.; Shanxi Medical University-BGI Collaborative Center for Future Medicine, Shanxi Medical University, Taiyuan, China.; Shenzhen Key Laboratory of Transomics Biotechnologies, BGI Research, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Loh+M%22">Loh M</searchLink>; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chambers+J%22">Chambers J</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Hon+CC%22">Hon CC</searchLink>; Laboratory for Genome Information Analysis, RIKEN Center for Integrative Medical Sciences, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Japan.<br /><searchLink fieldCode="AU" term="%22Choi+M%22">Choi M</searchLink>; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+JE%22">Park JE</searchLink>; Graduate School of Medical Science and Engineering, KAIST, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Ishigaki+K%22">Ishigaki K</searchLink>; Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.<br /><searchLink fieldCode="AU" term="%22Okamura+T%22">Okamura T</searchLink>; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Fujio+K%22">Fujio K</searchLink>; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Okada+Y%22">Okada Y</searchLink>; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan.; Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), Osaka University, Suita, Japan.<br /><searchLink fieldCode="AU" term="%22Park+WY%22">Park WY</searchLink>; Samsung Genome Institute, Samsung Medical Center, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Shin+JW%22">Shin JW</searchLink>; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Laboratory for Advanced Genomics Circuit, RIKEN Center for Integrative Medical Sciences, Yokohama City, Japan.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Roca+X%22">Roca X</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Prabhakar+S%22">Prabhakar S</searchLink>; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+B%22">Liu B</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg.; Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg.; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. boxiangliu@nus.edu.sg.; Precision Medicine Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg.; Cardiovascular-Metabolic Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. boxiangliu@nus.edu.sg. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Asian+Immune+Diversity+Atlas+Network%22">Asian Immune Diversity Atlas Network</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2024 Dec; Vol. 56 (12), pp. 2739-2752. <i>Date of Electronic Publication: </i>2024 Dec 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Co%22">Nature Pub. 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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39627432 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41588-024-02019-8 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2739 Titles: – TitleFull: Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tian C – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Tong Y – PersonEntity: Name: NameFull: Kock KH – PersonEntity: Name: NameFull: Sim DY – PersonEntity: Name: NameFull: Liu F – PersonEntity: Name: NameFull: Dong J – PersonEntity: Name: NameFull: Jing Z – PersonEntity: Name: NameFull: Wang W – PersonEntity: Name: NameFull: Gao J – PersonEntity: Name: NameFull: Tan LM – PersonEntity: Name: NameFull: Han KY – PersonEntity: Name: NameFull: Tomofuji Y – PersonEntity: Name: NameFull: Nakano M – PersonEntity: Name: NameFull: Buyamin EV – PersonEntity: Name: NameFull: Sonthalia R – PersonEntity: Name: NameFull: Ando Y – PersonEntity: Name: NameFull: Hatano H – PersonEntity: Name: NameFull: Sonehara K – PersonEntity: Name: NameFull: Jin X – PersonEntity: Name: NameFull: Loh M – PersonEntity: Name: NameFull: Chambers J – PersonEntity: Name: NameFull: Hon CC – PersonEntity: Name: NameFull: Choi M – PersonEntity: Name: NameFull: Park JE – PersonEntity: Name: NameFull: Ishigaki K – PersonEntity: Name: NameFull: Okamura T – PersonEntity: Name: NameFull: Fujio K – PersonEntity: Name: NameFull: Okada Y – PersonEntity: Name: NameFull: Park WY – PersonEntity: Name: NameFull: Shin JW – PersonEntity: Name: NameFull: Roca X – PersonEntity: Name: NameFull: Prabhakar S – PersonEntity: Name: NameFull: Liu B IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2024 Dec Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1546-1718 Numbering: – Type: volume Value: 56 – Type: issue Value: 12 Titles: – TitleFull: Nature genetics Type: main |
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