Bioinformatics and molecular docking reveal Cryptotanshinone as the active anti-inflammation component of Qu-Shi-Xie-Zhuo decoction by inhibiting S100A8/A9-NLRP3-IL-1β signaling.

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Title: Bioinformatics and molecular docking reveal Cryptotanshinone as the active anti-inflammation component of Qu-Shi-Xie-Zhuo decoction by inhibiting S100A8/A9-NLRP3-IL-1β signaling.
Authors: Liao XZ; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China., Xie RX; Department of Traditional Chinese Internal Medicine, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, PR China., Zheng SY; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China., Fan CL; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China., Zuo MY; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China., Chen SX; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China., Zhu JQ; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China. Electronic address: jqzhujq@yeah.net., Li J; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China; Department of Traditional Chinese Internal Medicine, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, PR China. Electronic address: lijuan@smu.edu.cn.
Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Jan; Vol. 136, pp. 156257. Date of Electronic Publication: 2024 Nov 26.
Publication Type: Journal Article
Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bioinformatics and molecular docking reveal Cryptotanshinone as the active anti-inflammation component of Qu-Shi-Xie-Zhuo decoction by inhibiting S100A8/A9-NLRP3-IL-1β signaling.
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  Data: <searchLink fieldCode="AU" term="%22Liao+XZ%22">Liao XZ</searchLink>; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Xie+RX%22">Xie RX</searchLink>; Department of Traditional Chinese Internal Medicine, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Zheng+SY%22">Zheng SY</searchLink>; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Fan+CL%22">Fan CL</searchLink>; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Zuo+MY%22">Zuo MY</searchLink>; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+SX%22">Chen SX</searchLink>; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Zhu+JQ%22">Zhu JQ</searchLink>; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China. Electronic address: jqzhujq@yeah.net.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China; Department of Traditional Chinese Internal Medicine, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, PR China. Electronic address: lijuan@smu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229438794%22">Phytomedicine : international journal of phytotherapy and phytopharmacology</searchLink> [Phytomedicine] 2025 Jan; Vol. 136, pp. 156257. <i>Date of Electronic Publication: </i>2024 Nov 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Urban+%26+Fischer+Verlag%22">Urban & Fischer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9438794 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1618-095X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209447113%22">09447113 </searchLink><i>NLM ISO Abbreviation: </i>Phytomedicine <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.phymed.2024.156257
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        Text: English
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      – TitleFull: Bioinformatics and molecular docking reveal Cryptotanshinone as the active anti-inflammation component of Qu-Shi-Xie-Zhuo decoction by inhibiting S100A8/A9-NLRP3-IL-1β signaling.
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              Text: 2025 Jan
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