How J-chain ensures the assembly of immunoglobulin IgM pentamers.

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Title: How J-chain ensures the assembly of immunoglobulin IgM pentamers.
Authors: Giannone C; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy. giannone@mit.edu.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, USA. giannone@mit.edu., Mess X; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., He R; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Chelazzi MR; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy., Mayer A; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Bakunts A; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy., Nguyen T; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Bushman Y; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Orsi A; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy., Gansen B; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy.; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Degano M; Division of Immunology and Infectious Diseases. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy., Buchner J; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany. johannes.buchner@tum.de., Sitia R; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy. sitia.roberto@hsr.it.
Source: The EMBO journal [EMBO J] 2025 Jan; Vol. 44 (2), pp. 505-533. Date of Electronic Publication: 2024 Dec 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1460-2075
DOI:10.1038/s44318-024-00317-9