Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists. - Glögl M; Krishnakumar A; Ragotte RJ; Goreshnik I; Coventry B; Bera AK; Kang A; Joyce E; Ahn G; Huang B; Yang W; Chen W; et al. (Science (New York, N.Y.), 2024)