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The dynamics of hematopoiesis over the human lifespan.

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Title: The dynamics of hematopoiesis over the human lifespan.
Authors: Li H; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. hojun@health.ucsd.edu.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA. hojun@health.ucsd.edu.; Harvard Medical School, Boston, MA, USA. hojun@health.ucsd.edu.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. hojun@health.ucsd.edu.; Department of Pediatrics, University of California, San Diego, CA, USA. hojun@health.ucsd.edu.; Division of Hematology/Oncology, Rady Children's Hospital, San Diego, CA, USA. hojun@health.ucsd.edu., Côté P; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Pediatrics, University of California, San Diego, CA, USA., Kuoch M; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Ezike J; Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Frenis K; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Afanassiev A; Department of Mathematics, University of British Columbia, Vancouver, British Columbia, Canada., Greenstreet L; Department of Mathematics, University of British Columbia, Vancouver, British Columbia, Canada., Tanaka-Yano M; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Tarantino G; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Zhang S; Department of Mathematics, University of British Columbia, Vancouver, British Columbia, Canada., Whangbo J; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Vor Biopharma, Cambridge, MA, USA., Butty VL; Barbara K. Ostrom Bioinformatics Facility, Integrated Genomics and Bioinformatics Core of the Koch Institute, Cambridge, MA, USA., Moiso E; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Falchetti M; Departments of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianopolis, Brazil., Lu K; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Connelly GG; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Morris V; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Wang D; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Chen AF; Harvard Medical School, Boston, MA, USA.; Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, MA, USA., Bianchi G; Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Daley GQ; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Garg S; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Liu D; Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Chou ST; Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Regev A; Division of Hematology/Oncology, Rady Children's Hospital, San Diego, CA, USA.; Genentech, South San Francisco, CA, USA., Lummertz da Rocha E; Departments of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianopolis, Brazil., Schiebinger G; Department of Mathematics, University of British Columbia, Vancouver, British Columbia, Canada., Rowe RG; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. grant_rowe@dfci.harvard.edu.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA. grant_rowe@dfci.harvard.edu.; Harvard Medical School, Boston, MA, USA. grant_rowe@dfci.harvard.edu.
Source: Nature methods [Nat Methods] 2025 Feb; Vol. 22 (2), pp. 422-434. Date of Electronic Publication: 2024 Dec 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. hojun@health.ucsd.edu.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA. hojun@health.ucsd.edu.; Harvard Medical School, Boston, MA, USA. hojun@health.ucsd.edu.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. hojun@health.ucsd.edu.; Department of Pediatrics, University of California, San Diego, CA, USA. hojun@health.ucsd.edu.; Division of Hematology/Oncology, Rady Children's Hospital, San Diego, CA, USA. hojun@health.ucsd.edu.<br /><searchLink fieldCode="AU" term="%22Côté+P%22">Côté P</searchLink>; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Pediatrics, University of California, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kuoch+M%22">Kuoch M</searchLink>; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ezike+J%22">Ezike J</searchLink>; Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Frenis+K%22">Frenis K</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Afanassiev+A%22">Afanassiev A</searchLink>; Department of Mathematics, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Greenstreet+L%22">Greenstreet L</searchLink>; Department of Mathematics, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Tanaka-Yano+M%22">Tanaka-Yano M</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tarantino+G%22">Tarantino G</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Mathematics, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Whangbo+J%22">Whangbo J</searchLink>; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Vor Biopharma, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Butty+VL%22">Butty VL</searchLink>; Barbara K. 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