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An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology.

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Title: An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology.
Authors: Sokolowski DJ; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Ontario Institute for Cancer Research (OICR), Toronto, ON, Canada., Miclăuș M; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Molecular Neuroscience, Transylvanian Institute of Neuroscience, Cluj-Napoca, Romania., Nater A; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland., Faykoo-Martinez M; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Psychology, University of Toronto Mississauga, Toronto, ON, Canada.; Department of Cell and Systems Biology, University of Toronto Mississauga, Toronto, ON, Canada., Hoekzema K; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA., Zuzarte P; Ontario Institute for Cancer Research (OICR), Toronto, ON, Canada., Monis S; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Alvi SA; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada., Erdmann J; GeneCode Healthcare, LLC, Mountain View, CA, USA., Erdmann AL; GeneCode Healthcare, LLC, Mountain View, CA, USA., Kumaragurubaran R; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Pediatrics University of Cincinnati College of Medicine, Cincinnati, OH, USA.; University Health Network (UHN), Toronto, ON, Canada., Bayerl J; Department of Ob/Gyn, Bakar Aging Research Institute, Institute of Regeneration Medicine, University of California San Francisco., Yoo D; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA., Karimpour N; Department of Molecular Neuroscience, Transylvanian Institute of Neuroscience, Cluj-Napoca, Romania.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Ungerleider K; Department of Molecular Neuroscience, Transylvanian Institute of Neuroscience, Cluj-Napoca, Romania.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Hou H; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada., J Martin F; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Hourlier T; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Clarke Z; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Lischer HEL; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland., Leordean DV; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Molecular Neuroscience, Transylvanian Institute of Neuroscience, Cluj-Napoca, Romania., Jiang Y; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Pugh TJ; Ontario Institute for Cancer Research (OICR), Toronto, ON, Canada.; University Health Network (UHN), Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Smith ESJ; Department of Pharmacology, University of Cambridge, Cambridge, UK., Haggerty L; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Laird DJ; Department of Ob/Gyn, Bakar Aging Research Institute, Institute of Regeneration Medicine, University of California San Francisco., Lilue J; Oujiang Laboratory, Wenzhou, China., Holmes MM; Department of Psychology, University of Toronto Mississauga, Toronto, ON, Canada.; Department of Cell and Systems Biology, University of Toronto Mississauga, Toronto, ON, Canada., Eichler EE; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.; HHMI, University of Washington, Seattle, WA, USA., Bruggmann R; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland., Simpson JT; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Ontario Institute for Cancer Research (OICR), Toronto, ON, Canada., Balmus G; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Molecular Neuroscience, Transylvanian Institute of Neuroscience, Cluj-Napoca, Romania.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Wilson MD; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 28. Date of Electronic Publication: 2024 Nov 28.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Department of Cell and Systems Biology, University of Toronto Mississauga, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Hoekzema+K%22">Hoekzema K</searchLink>; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Zuzarte+P%22">Zuzarte P</searchLink>; Ontario Institute for Cancer Research (OICR), Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Monis+S%22">Monis S</searchLink>; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Alvi+SA%22">Alvi SA</searchLink>; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Erdmann+J%22">Erdmann J</searchLink>; GeneCode Healthcare, LLC, Mountain View, CA, USA.<br /><searchLink fieldCode="AU" term="%22Erdmann+AL%22">Erdmann AL</searchLink>; GeneCode Healthcare, LLC, Mountain View, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kumaragurubaran+R%22">Kumaragurubaran R</searchLink>; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Pediatrics University of Cincinnati College of Medicine, Cincinnati, OH, USA.; University Health Network (UHN), Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Bayerl+J%22">Bayerl J</searchLink>; Department of Ob/Gyn, Bakar Aging Research Institute, Institute of Regeneration Medicine, University of California San Francisco.<br /><searchLink fieldCode="AU" term="%22Yoo+D%22">Yoo D</searchLink>; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Karimpour+N%22">Karimpour N</searchLink>; Department of Molecular Neuroscience, Transylvanian Institute of Neuroscience, Cluj-Napoca, Romania.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ungerleider+K%22">Ungerleider K</searchLink>; 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Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Leordean+DV%22">Leordean DV</searchLink>; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Molecular Neuroscience, Transylvanian Institute of Neuroscience, Cluj-Napoca, Romania.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Pugh+TJ%22">Pugh TJ</searchLink>; Ontario Institute for Cancer Research (OICR), Toronto, ON, Canada.; University Health Network (UHN), Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Smith+ESJ%22">Smith ESJ</searchLink>; Department of Pharmacology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Haggerty+L%22">Haggerty L</searchLink>; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Laird+DJ%22">Laird DJ</searchLink>; Department of Ob/Gyn, Bakar Aging Research Institute, Institute of Regeneration Medicine, University of California San Francisco.<br /><searchLink fieldCode="AU" term="%22Lilue+J%22">Lilue J</searchLink>; Oujiang Laboratory, Wenzhou, China.<br /><searchLink fieldCode="AU" term="%22Holmes+MM%22">Holmes MM</searchLink>; Department of Psychology, University of Toronto Mississauga, Toronto, ON, Canada.; Department of Cell and Systems Biology, University of Toronto Mississauga, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Eichler+EE%22">Eichler EE</searchLink>; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.; HHMI, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Bruggmann+R%22">Bruggmann R</searchLink>; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Simpson+JT%22">Simpson JT</searchLink>; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Ontario Institute for Cancer Research (OICR), Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Balmus+G%22">Balmus G</searchLink>; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Molecular Neuroscience, Transylvanian Institute of Neuroscience, Cluj-Napoca, Romania.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Wilson+MD%22">Wilson MD</searchLink>; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
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