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Results from a Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Crossover Trial of Lovastatin or Minocycline in Fragile X Syndrome.

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Title: Results from a Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Crossover Trial of Lovastatin or Minocycline in Fragile X Syndrome.
Authors: McKinney WS; Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Schmitt LM; Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., De Stefano LA; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Ethridge L; Department of Psychology, University of Oklahoma, Norman, Oklahoma, USA.; Department of Pediatrics, Section of Developmental and Behavioral Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Norris JE; Department of Psychology, University of Oklahoma, Norman, Oklahoma, USA., Horn PS; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Dauterman S; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Neuroscience Graduate Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Rosselot H; National Fragile X Foundation, Washington, DC, USA., Pedapati EV; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Reisinger DL; Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Dominick KC; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Shaffer RC; Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Chin D; The Heidt Center of Excellence, Cincinnati, Ohio, USA., Friedman NR; Department of Psychology, University of Alabama, Tuscaloosa, Alabama, USA., Hong M; Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Sweeney JA; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Erickson C; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Source: Journal of child and adolescent psychopharmacology [J Child Adolesc Psychopharmacol] 2025 May; Vol. 35 (4), pp. 211-221. Date of Electronic Publication: 2024 Dec 09.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 9105358 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8992 (Electronic) Linking ISSN: 10445463 NLM ISO Abbreviation: J Child Adolesc Psychopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Results from a Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Crossover Trial of Lovastatin or Minocycline in Fragile X Syndrome.
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  Data: <searchLink fieldCode="AU" term="%22McKinney+WS%22">McKinney WS</searchLink>; Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Schmitt+LM%22">Schmitt LM</searchLink>; Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22De+Stefano+LA%22">De Stefano LA</searchLink>; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Ethridge+L%22">Ethridge L</searchLink>; Department of Psychology, University of Oklahoma, Norman, Oklahoma, USA.; Department of Pediatrics, Section of Developmental and Behavioral Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Norris+JE%22">Norris JE</searchLink>; Department of Psychology, University of Oklahoma, Norman, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Horn+PS%22">Horn PS</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Dauterman+S%22">Dauterman S</searchLink>; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Neuroscience Graduate Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Rosselot+H%22">Rosselot H</searchLink>; National Fragile X Foundation, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Pedapati+EV%22">Pedapati EV</searchLink>; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Reisinger+DL%22">Reisinger DL</searchLink>; Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Dominick+KC%22">Dominick KC</searchLink>; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Shaffer+RC%22">Shaffer RC</searchLink>; Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Chin+D%22">Chin D</searchLink>; The Heidt Center of Excellence, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Friedman+NR%22">Friedman NR</searchLink>; Department of Psychology, University of Alabama, Tuscaloosa, Alabama, USA.<br /><searchLink fieldCode="AU" term="%22Hong+M%22">Hong M</searchLink>; Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Sweeney+JA%22">Sweeney JA</searchLink>; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Erickson+C%22">Erickson C</searchLink>; Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
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  Data: <searchLink fieldCode="JN" term="%229105358%22">Journal of child and adolescent psychopharmacology</searchLink> [J Child Adolesc Psychopharmacol] 2025 May; Vol. 35 (4), pp. 211-221. <i>Date of Electronic Publication: </i>2024 Dec 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mary+Ann+Liebert%22">Mary Ann Liebert </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9105358 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-8992 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210445463%22">10445463 </searchLink><i>NLM ISO Abbreviation: </i>J Child Adolesc Psychopharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1089/cap.2024.0103
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        Text: English
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        StartPage: 211
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      – TitleFull: Results from a Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Crossover Trial of Lovastatin or Minocycline in Fragile X Syndrome.
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