View in EDS

Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation.

Saved in:
Bibliographic Details
Title: Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation.
Authors: Shah V; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany., Giotopoulos G; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Osaki H; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Meyerhöfer M; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany., Meduri E; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Gallego-Crespo A; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany., Behrendt MA; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany., Saura-Pañella M; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany., Tarkar A; GlaxoSmithKline Research and Development, Collegeville, PA., Schubert B; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany., Yun H; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; Department of Medicine V, Hematology, Oncology, and Rheumatology, University of Heidelberg, Heidelberg, Germany., Horton SJ; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Agrawal-Singh S; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Haehnel PS; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany., Basheer F; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Lugo D; Adaptive Immunity and Immuno-epigenetics Research Unit, GlaxoSmithKline Research and Development, Stevenage, United Kingdom., Eleftheriadou I; GlaxoSmithKline Research and Development, Collegeville, PA., Barbash O; GlaxoSmithKline Research and Development, Collegeville, PA., Dhar A; GlaxoSmithKline Research and Development, Collegeville, PA., Kühn MWM; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany., Guezguez B; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany., Theobald M; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany., Kindler T; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany., Gallipoli P; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Yeh P; Monash Haematology, Monash Health and School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia., Dawson MA; Department of Clinical Haematology, Peter MacCallum Cancer Centre, Melbourne, Australia., Prinjha RK; Adaptive Immunity and Immuno-epigenetics Research Unit, GlaxoSmithKline Research and Development, Stevenage, United Kingdom., Huntly BJP; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Sasca D; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany.; Institute for Quantitative and Computational Biosciences, Johannes Gutenberg University, Mainz, Germany.
Source: Blood [Blood] 2025 Feb 13; Vol. 145 (7), pp. 748-764.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39651888
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Shah+V%22">Shah V</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Giotopoulos+G%22">Giotopoulos G</searchLink>; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Osaki+H%22">Osaki H</searchLink>; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Meyerhöfer+M%22">Meyerhöfer M</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Meduri+E%22">Meduri E</searchLink>; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gallego-Crespo+A%22">Gallego-Crespo A</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Behrendt+MA%22">Behrendt MA</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Saura-Pañella+M%22">Saura-Pañella M</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Tarkar+A%22">Tarkar A</searchLink>; GlaxoSmithKline Research and Development, Collegeville, PA.<br /><searchLink fieldCode="AU" term="%22Schubert+B%22">Schubert B</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Yun+H%22">Yun H</searchLink>; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; Department of Medicine V, Hematology, Oncology, and Rheumatology, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Horton+SJ%22">Horton SJ</searchLink>; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Agrawal-Singh+S%22">Agrawal-Singh S</searchLink>; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Haehnel+PS%22">Haehnel PS</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Basheer+F%22">Basheer F</searchLink>; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lugo+D%22">Lugo D</searchLink>; Adaptive Immunity and Immuno-epigenetics Research Unit, GlaxoSmithKline Research and Development, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Eleftheriadou+I%22">Eleftheriadou I</searchLink>; GlaxoSmithKline Research and Development, Collegeville, PA.<br /><searchLink fieldCode="AU" term="%22Barbash+O%22">Barbash O</searchLink>; GlaxoSmithKline Research and Development, Collegeville, PA.<br /><searchLink fieldCode="AU" term="%22Dhar+A%22">Dhar A</searchLink>; GlaxoSmithKline Research and Development, Collegeville, PA.<br /><searchLink fieldCode="AU" term="%22Kühn+MWM%22">Kühn MWM</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Guezguez+B%22">Guezguez B</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Theobald+M%22">Theobald M</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Kindler+T%22">Kindler T</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Gallipoli+P%22">Gallipoli P</searchLink>; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Yeh+P%22">Yeh P</searchLink>; Monash Haematology, Monash Health and School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Dawson+MA%22">Dawson MA</searchLink>; Department of Clinical Haematology, Peter MacCallum Cancer Centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Prinjha+RK%22">Prinjha RK</searchLink>; Adaptive Immunity and Immuno-epigenetics Research Unit, GlaxoSmithKline Research and Development, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Huntly+BJP%22">Huntly BJP</searchLink>; Cambridge Stem Cell Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sasca+D%22">Sasca D</searchLink>; Department of Hematology and Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; University Cancer Center, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; German Cancer Consortium, Mainz, Germany.; Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany.; Institute for Quantitative and Computational Biosciences, Johannes Gutenberg University, Mainz, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2025 Feb 13; Vol. 145 (7), pp. 748-764.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7603509 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-0020 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200064971%22">00064971 </searchLink><i>NLM ISO Abbreviation: </i>Blood <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39651888
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1182/blood.2022019306
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 748
    Titles:
      – TitleFull: Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Shah V
      – PersonEntity:
          Name:
            NameFull: Giotopoulos G
      – PersonEntity:
          Name:
            NameFull: Osaki H
      – PersonEntity:
          Name:
            NameFull: Meyerhöfer M
      – PersonEntity:
          Name:
            NameFull: Meduri E
      – PersonEntity:
          Name:
            NameFull: Gallego-Crespo A
      – PersonEntity:
          Name:
            NameFull: Behrendt MA
      – PersonEntity:
          Name:
            NameFull: Saura-Pañella M
      – PersonEntity:
          Name:
            NameFull: Tarkar A
      – PersonEntity:
          Name:
            NameFull: Schubert B
      – PersonEntity:
          Name:
            NameFull: Yun H
      – PersonEntity:
          Name:
            NameFull: Horton SJ
      – PersonEntity:
          Name:
            NameFull: Agrawal-Singh S
      – PersonEntity:
          Name:
            NameFull: Haehnel PS
      – PersonEntity:
          Name:
            NameFull: Basheer F
      – PersonEntity:
          Name:
            NameFull: Lugo D
      – PersonEntity:
          Name:
            NameFull: Eleftheriadou I
      – PersonEntity:
          Name:
            NameFull: Barbash O
      – PersonEntity:
          Name:
            NameFull: Dhar A
      – PersonEntity:
          Name:
            NameFull: Kühn MWM
      – PersonEntity:
          Name:
            NameFull: Guezguez B
      – PersonEntity:
          Name:
            NameFull: Theobald M
      – PersonEntity:
          Name:
            NameFull: Kindler T
      – PersonEntity:
          Name:
            NameFull: Gallipoli P
      – PersonEntity:
          Name:
            NameFull: Yeh P
      – PersonEntity:
          Name:
            NameFull: Dawson MA
      – PersonEntity:
          Name:
            NameFull: Prinjha RK
      – PersonEntity:
          Name:
            NameFull: Huntly BJP
      – PersonEntity:
          Name:
            NameFull: Sasca D
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 13
              M: 02
              Text: 2025 Feb 13
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1528-0020
          Numbering:
            – Type: volume
              Value: 145
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Blood
              Type: main
ResultId 1