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In Situ Tracking of TCRβ Isoforms for Detection of T Cell Clonality: Implication for Precision Diagnosis and Targeted Immunotherapy of T-Cell Neoplasms.

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Title: In Situ Tracking of TCRβ Isoforms for Detection of T Cell Clonality: Implication for Precision Diagnosis and Targeted Immunotherapy of T-Cell Neoplasms.
Authors: Manipadam MT; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK., Marra A; Department of Medicine and Surgery, Laboratory of Molecular Medicine and Biotechnology, University Campus Bio-Medico of Rome, Rome, Italy.; Institute of Translational Pharmacology, National Research Council of Italy (CNR), Rome, Italy., Ramsay A; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK., Padmasri S; Department Research Pathology, Cancer Institute, University College London, London, UK., Gosh A; Department Research Pathology, Cancer Institute, University College London, London, UK., Neves M; Department Research Pathology, Cancer Institute, University College London, London, UK., Bailey C; Department of Clinical Haematology, University College Hospitals London, London, UK., Pomplun S; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK., Maciocia P; Research Department of Haematology, Cancer Institute, University College London, London, UK.; Autolus Ltd, London, UK., Cwynarski K; Department of Clinical Haematology, University College Hospitals London, London, UK., Ferrari M; Autolus Ltd, London, UK., Lao-Siriex P; Autolus Ltd, London, UK., Piris M; Pathology Department, lnstituto de lnvestigacion Sanitaria Fundacion Jimenez Diaz, Madrid, Spain., Falini B; Institute of Haematology and Center for Haemato-Oncological Research (CREO), University of Perugia and Santa Maria della Misericordia Hospital, Perugia, Italy., Linch D; Research Department of Haematology, Cancer Institute, University College London, London, UK., Rosenwald A; Institute of Pathology, University of Würzburg, Würzburg, Germany., Pule M; Research Department of Haematology, Cancer Institute, University College London, London, UK., Zamò A; Institute of Pathology, University of Würzburg, Würzburg, Germany., Marafioti T; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK.; Department Research Pathology, Cancer Institute, University College London, London, UK.
Source: Hematological oncology [Hematol Oncol] 2025 Jan; Vol. 43 (1), pp. e70018.
Publication Type: Letter
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8307268 Publication Model: Print Cited Medium: Internet ISSN: 1099-1069 (Electronic) Linking ISSN: 02780232 NLM ISO Abbreviation: Hematol Oncol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: In Situ Tracking of TCRβ Isoforms for Detection of T Cell Clonality: Implication for Precision Diagnosis and Targeted Immunotherapy of T-Cell Neoplasms.
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  Data: <searchLink fieldCode="AU" term="%22Manipadam+MT%22">Manipadam MT</searchLink>; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Marra+A%22">Marra A</searchLink>; Department of Medicine and Surgery, Laboratory of Molecular Medicine and Biotechnology, University Campus Bio-Medico of Rome, Rome, Italy.; Institute of Translational Pharmacology, National Research Council of Italy (CNR), Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ramsay+A%22">Ramsay A</searchLink>; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Padmasri+S%22">Padmasri S</searchLink>; Department Research Pathology, Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gosh+A%22">Gosh A</searchLink>; Department Research Pathology, Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Neves+M%22">Neves M</searchLink>; Department Research Pathology, Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bailey+C%22">Bailey C</searchLink>; Department of Clinical Haematology, University College Hospitals London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pomplun+S%22">Pomplun S</searchLink>; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Maciocia+P%22">Maciocia P</searchLink>; Research Department of Haematology, Cancer Institute, University College London, London, UK.; Autolus Ltd, London, UK.<br /><searchLink fieldCode="AU" term="%22Cwynarski+K%22">Cwynarski K</searchLink>; Department of Clinical Haematology, University College Hospitals London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ferrari+M%22">Ferrari M</searchLink>; Autolus Ltd, London, UK.<br /><searchLink fieldCode="AU" term="%22Lao-Siriex+P%22">Lao-Siriex P</searchLink>; Autolus Ltd, London, UK.<br /><searchLink fieldCode="AU" term="%22Piris+M%22">Piris M</searchLink>; Pathology Department, lnstituto de lnvestigacion Sanitaria Fundacion Jimenez Diaz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Falini+B%22">Falini B</searchLink>; Institute of Haematology and Center for Haemato-Oncological Research (CREO), University of Perugia and Santa Maria della Misericordia Hospital, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Linch+D%22">Linch D</searchLink>; Research Department of Haematology, Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Rosenwald+A%22">Rosenwald A</searchLink>; Institute of Pathology, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Pule+M%22">Pule M</searchLink>; Research Department of Haematology, Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Zamò+A%22">Zamò A</searchLink>; Institute of Pathology, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Marafioti+T%22">Marafioti T</searchLink>; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK.; Department Research Pathology, Cancer Institute, University College London, London, UK.
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