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Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity.

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Title: Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity.
Authors: Cui YH; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637., Wei J; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637., Fan H; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL 60637., Li W; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637., Zhao L; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637., Wilkinson E; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637.; Committee on Cancer Biology, University of Chicago, Chicago, IL 60637., Peterson J; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637.; The College, University of Chicago, Chicago, IL 60637., Xie L; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL 60637., Zou Z; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637., Yang S; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637., Applebaum MA; Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637., Kline J; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL 60637., Chen J; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL 60637., He C; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637.; HHMI, University of Chicago, Chicago, IL 60637., He YY; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Dec 17; Vol. 121 (51), pp. e2407910121. Date of Electronic Publication: 2024 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity.
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  Data: <searchLink fieldCode="AU" term="%22Cui+YH%22">Cui YH</searchLink>; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Wei+J%22">Wei J</searchLink>; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Fan+H%22">Fan H</searchLink>; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Wilkinson+E%22">Wilkinson E</searchLink>; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637.; Committee on Cancer Biology, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Peterson+J%22">Peterson J</searchLink>; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637.; The College, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Xie+L%22">Xie L</searchLink>; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Zou+Z%22">Zou Z</searchLink>; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Applebaum+MA%22">Applebaum MA</searchLink>; Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Kline+J%22">Kline J</searchLink>; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22He+C%22">He C</searchLink>; Departments of Chemistry, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637.; Department of Biochemistry and Molecular Biology Institute for Biophysical Dynamics University of Chicago, Chicago, IL 60637.; HHMI, University of Chicago, Chicago, IL 60637.<br /><searchLink fieldCode="AU" term="%22He+YY%22">He YY</searchLink>; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637.
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