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The Influence of Pharmacogenetic Factors on the Pharmacokinetics of Morphine and Its Metabolites in Pediatric Patients: A Systematic Review.

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Title: The Influence of Pharmacogenetic Factors on the Pharmacokinetics of Morphine and Its Metabolites in Pediatric Patients: A Systematic Review.
Authors: Mufti K; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Juárez-Hernández JE; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Gheshlaghi N; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Pharmaceutical Outcomes Program, British Columbia Children's Hospital, Vancouver, British Columbia, Canada.; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Lovnicki JM; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Pharmaceutical Outcomes Program, British Columbia Children's Hospital, Vancouver, British Columbia, Canada., Rassekh SR; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Oncology, Hematology & Bone Marrow Transplant, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Ross CJD; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Carleton BC; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Pharmaceutical Outcomes Program, British Columbia Children's Hospital, Vancouver, British Columbia, Canada., Loucks CM; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Anesthesiology, Pharmacology & Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Source: Anesthesia and analgesia [Anesth Analg] 2025 Sep 01; Vol. 141 (3), pp. 550-559. Date of Electronic Publication: 2024 Dec 11.
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 1310650 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-7598 (Electronic) Linking ISSN: 00032999 NLM ISO Abbreviation: Anesth Analg Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Mufti+K%22">Mufti K</searchLink>; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Juárez-Hernández+JE%22">Juárez-Hernández JE</searchLink>; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Gheshlaghi+N%22">Gheshlaghi N</searchLink>; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Pharmaceutical Outcomes Program, British Columbia Children's Hospital, Vancouver, British Columbia, Canada.; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Lovnicki+JM%22">Lovnicki JM</searchLink>; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Pharmaceutical Outcomes Program, British Columbia Children's Hospital, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Rassekh+SR%22">Rassekh SR</searchLink>; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Oncology, Hematology & Bone Marrow Transplant, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Ross+CJD%22">Ross CJD</searchLink>; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Carleton+BC%22">Carleton BC</searchLink>; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Pharmaceutical Outcomes Program, British Columbia Children's Hospital, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Loucks+CM%22">Loucks CM</searchLink>; From the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Anesthesiology, Pharmacology & Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
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        Value: 10.1213/ANE.0000000000007349
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        Text: English
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              Text: 2025 Sep 01
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