AR alterations inform circulating tumor DNA detection in metastatic castration resistant prostate cancer patients.

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Title: AR alterations inform circulating tumor DNA detection in metastatic castration resistant prostate cancer patients.
Authors: Knutson TP; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA., Luo B; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA., Kobilka A; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Lyman J; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Graduate Program in Molecular, Cellular, and Developmental Biology and Genetics, University of Minnesota, Minneapolis, MN, USA., Guo S; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA., Munro SA; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA., Li Y; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Heer R; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, Tyne and Wear, UK.; Translational and Clinical Research Institute, NU Cancer, Newcastle upon Tyne, Tyne and Wear, UK., Gaughan L; Translational and Clinical Research Institute, NU Cancer, Newcastle upon Tyne, Tyne and Wear, UK., Morris MJ; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Beltran H; Department of Medical Oncology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Ryan CJ; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Antonarakis ES; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Armstrong AJ; Department of Medicine, Division of Medical Oncology, Duke Cancer Institute Center for Prostate and Urologic Cancers, Duke University, Durham, NC, USA., Halabi S; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA., Dehm SM; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA. dehm@umn.edu.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA. dehm@umn.edu.; Department of Urology, University of Minnesota, Minneapolis, MN, USA. dehm@umn.edu.
Source: Nature communications [Nat Commun] 2024 Dec 11; Vol. 15 (1), pp. 10648. Date of Electronic Publication: 2024 Dec 11.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Research Support, U.S. Gov't, P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-024-54847-1