Safety, Tolerability and Pharmacokinetics of Intravenous Sodium Taurodeoxycholate, HY209, a GPCR19 Agonist Inhibiting Inflammasomal Activation.

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Title: Safety, Tolerability and Pharmacokinetics of Intravenous Sodium Taurodeoxycholate, HY209, a GPCR19 Agonist Inhibiting Inflammasomal Activation.
Authors: Chung WK; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea., Jeon I; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea., Jang IJ; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea., Seong SY; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Han SA; Shaperon Inc, Seoul, Republic of Korea., Yu KS; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2024 Dec 08; Vol. 18, pp. 5853-5861. Date of Electronic Publication: 2024 Dec 08 (Print Publication: 2024).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1177-8881
DOI:10.2147/DDDT.S438507