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Pharmacodynamics of the orexin type 1 (OX1) receptor in colon cancer cell models: A two-sided nature of antagonistic ligands resulting from partial dissociation of Gq.

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Title: Pharmacodynamics of the orexin type 1 (OX1) receptor in colon cancer cell models: A two-sided nature of antagonistic ligands resulting from partial dissociation of Gq.
Authors: Gratio V; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France.; INSERM UMR1149/Inflammation Research Center (CRI), Flow Cytometry Platform (CytoCRI), DHU UNITY, Université Paris Cité, Paris, France., Dragan P; Faculty of Chemistry, University of Warsaw, Warsaw, Poland., Garcia L; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France., Saveanu L; INSERM UMR1149/Inflammation Research Center (CRI), Team 'Antigen Presentation by Dendritic Cells to T cells (APreT)', DHU UNITY, Université Paris Cité, Paris, France., Nicole P; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France., Voisin T; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France., Latek D; Faculty of Chemistry, University of Warsaw, Warsaw, Poland., Couvineau A; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France.
Source: British journal of pharmacology [Br J Pharmacol] 2025 Apr; Vol. 182 (7), pp. 1528-1545. Date of Electronic Publication: 2024 Dec 15.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacodynamics of the orexin type 1 (OX<subscript>1</subscript>) receptor in colon cancer cell models: A two-sided nature of antagonistic ligands resulting from partial dissociation of Gq.
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  Data: <searchLink fieldCode="AU" term="%22Gratio+V%22">Gratio V</searchLink>; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France.; INSERM UMR1149/Inflammation Research Center (CRI), Flow Cytometry Platform (CytoCRI), DHU UNITY, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Dragan+P%22">Dragan P</searchLink>; Faculty of Chemistry, University of Warsaw, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Garcia+L%22">Garcia L</searchLink>; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Saveanu+L%22">Saveanu L</searchLink>; INSERM UMR1149/Inflammation Research Center (CRI), Team 'Antigen Presentation by Dendritic Cells to T cells (APreT)', DHU UNITY, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Nicole+P%22">Nicole P</searchLink>; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Voisin+T%22">Voisin T</searchLink>; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Latek+D%22">Latek D</searchLink>; Faculty of Chemistry, University of Warsaw, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Couvineau+A%22">Couvineau A</searchLink>; INSERM UMR1149/Inflammation Research Center (CRI), Team 'From Inflammation to Cancer in Digestive diseases (INDiD)', DHU UNITY, Université Paris Cité, Paris, France.
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  Data: <searchLink fieldCode="JN" term="%227502536%22">British journal of pharmacology</searchLink> [Br J Pharmacol] 2025 Apr; Vol. 182 (7), pp. 1528-1545. <i>Date of Electronic Publication: </i>2024 Dec 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7502536 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5381 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071188%22">00071188 </searchLink><i>NLM ISO Abbreviation: </i>Br J Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1111/bph.17422
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              Text: 2025 Apr
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