Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases.
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| Title: | Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases. |
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| Authors: | Sundstrom J; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Vanderleeden E; Department of Medicine, Diabetes Center of Excellence, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Barton NJ; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Redick SD; Program in Molecular Medicine, Diabetes Center of Excellence, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Dawes P; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Murray LF; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Olson MN; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Tran K; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Graduate Program in Biochemistry & Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Chigas SM; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Graduate Program in Neuroscience, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Orszulak AR; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Graduate Program in Immunology and Microbiology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Church GM; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA., Readhead B; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ 85281, USA., Oh HS; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Harlan DM; Department of Medicine, Diabetes Center of Excellence, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Knipe DM; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Wang JP; Department of Medicine, Diabetes Center of Excellence, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Chan Y; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Lim ET; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA. |
| Source: | Cells [Cells] 2024 Nov 29; Vol. 13 (23). Date of Electronic Publication: 2024 Nov 29. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2073-4409 |
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| DOI: | 10.3390/cells13231978 |
