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Stem Cell Markers LGR5, LGR4 and Their Immediate Signalling Partners are Dysregulated in Preeclampsia.

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Title: Stem Cell Markers LGR5, LGR4 and Their Immediate Signalling Partners are Dysregulated in Preeclampsia.
Authors: Wong GP; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia. gpwong@student.unimelb.edu.au.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia. gpwong@student.unimelb.edu.au., Hartmann S; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.; Charité- Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a cooperation between the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association and Charitè Campus Buch, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; DZHK (German Center for Cardiovascular Research), partner site, Berlin, Germany., Nonn O; Charité- Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a cooperation between the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association and Charitè Campus Buch, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; DZHK (German Center for Cardiovascular Research), partner site, Berlin, Germany.; Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria., Cannon P; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia., Nguyen TV; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia., Kandel M; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia., de Alwis N; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia., Murphy CN; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia., Pritchard N; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia., Dechend R; Charité- Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a cooperation between the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association and Charitè Campus Buch, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; DZHK (German Center for Cardiovascular Research), partner site, Berlin, Germany.; Department of Cardiology and Nephrology, HELIOS Klinikum, Berlin Buch, Germany., Hannan NJ; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia., Tong S; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia., Simmons DG; School of Biomedical Sciences, University of Queensland, Brisbane, Australia., Kaitu'u-Lino TJ; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.
Source: Stem cell reviews and reports [Stem Cell Rev Rep] 2025 Apr; Vol. 21 (3), pp. 872-896. Date of Electronic Publication: 2024 Dec 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101752767 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2629-3277 (Electronic) Linking ISSN: 26293277 NLM ISO Abbreviation: Stem Cell Rev Rep Subsets: MEDLINE
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  Data: Stem Cell Markers LGR5, LGR4 and Their Immediate Signalling Partners are Dysregulated in Preeclampsia.
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  Data: <searchLink fieldCode="AU" term="%22Wong+GP%22">Wong GP</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia. gpwong@student.unimelb.edu.au.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia. gpwong@student.unimelb.edu.au.<br /><searchLink fieldCode="AU" term="%22Hartmann+S%22">Hartmann S</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.; Charité- Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a cooperation between the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association and Charitè Campus Buch, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; DZHK (German Center for Cardiovascular Research), partner site, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Nonn+O%22">Nonn O</searchLink>; Charité- Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a cooperation between the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association and Charitè Campus Buch, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; DZHK (German Center for Cardiovascular Research), partner site, Berlin, Germany.; Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Cannon+P%22">Cannon P</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Nguyen+TV%22">Nguyen TV</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Kandel+M%22">Kandel M</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22de+Alwis+N%22">de Alwis N</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Murphy+CN%22">Murphy CN</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Pritchard+N%22">Pritchard N</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Dechend+R%22">Dechend R</searchLink>; Charité- Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a cooperation between the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association and Charitè Campus Buch, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; DZHK (German Center for Cardiovascular Research), partner site, Berlin, Germany.; Department of Cardiology and Nephrology, HELIOS Klinikum, Berlin Buch, Germany.<br /><searchLink fieldCode="AU" term="%22Hannan+NJ%22">Hannan NJ</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Tong+S%22">Tong S</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Simmons+DG%22">Simmons DG</searchLink>; School of Biomedical Sciences, University of Queensland, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Kaitu'u-Lino+TJ%22">Kaitu'u-Lino TJ</searchLink>; The Department of Obstetrics, Gynaecology and Newborn Health/Mercy Hospital for Women, University of Melbourne, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.; Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia.
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