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Effectiveness of ceftazidime-avibactam versus ceftolozane-tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the USA (CACTUS): a multicentre, retrospective, observational study.

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Title: Effectiveness of ceftazidime-avibactam versus ceftolozane-tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the USA (CACTUS): a multicentre, retrospective, observational study.
Authors: Shields RK; Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA., Abbo LM; Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL, USA; Department of Infection Control and Antimicrobial Stewardship, Jackson Memorial Hospital, Miami, FL, USA., Ackley R; Atrium Health, Charlotte, NC, USA., Aitken SL; University of Michigan College of Pharmacy, Ann Arbor, MI, USA., Albrecht B; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA., Babiker A; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA., Burgoon R; Department of Pharmacy, Medical University of South Carolina (MUSC) Health, Charleston, SC, USA., Cifuentes R; University of Miami, Miller School of Medicine, Miami, FL, USA., Claeys KC; University of Maryland School of Pharmacy, Baltimore, MD, USA., Curry BN; University of Illinois Chicago College of Pharmacy, Chicago, IL, USA., DeSear KE; University of Florida Health Shands Hospital, Gainesville, FL, USA., Gallagher JC; Temple University School of Pharmacy, Philadelphia, PA, USA., Golnabi EY; University of Texas Southwestern Medical Center, Dallas, TX, USA., Gross AE; University of Illinois Chicago College of Pharmacy, Chicago, IL, USA., Hand J; Ochsner Health, New Orleans, LA, USA., Heil EL; University of Maryland School of Pharmacy, Baltimore, MD, USA., Hornback KM; Department of Pharmacy, Medical University of South Carolina (MUSC) Health, Charleston, SC, USA., Kaye KS; Division of Allergy, Immunology, and Infectious Diseases, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA., Khuu TV; Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC, USA., Klatt ME; The University of Kansas Health System, Kansas City, KS, USA., Kline EG; Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: ellenkline@pitt.edu., Kubat RC; The University of Kansas Health System, Kansas City, KS, USA., Kufel WD; Binghamton University School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Lee JH; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lepak AJ; University of Wisconsin School of Medicine and Public Health, Madison, WI, USA., Lim A; Department of Clinical Pharmacy, University of California, San Francisco, CA, USA., Ludwig JM; University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Macdougall C; Department of Clinical Pharmacy, University of California, San Francisco, CA, USA., Majumdar A; Division of Allergy, Immunology, and Infectious Diseases, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA., Mathers AJ; University of Virginia, Charlottesville, VA, USA., McCreary EK; Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA., Miller WR; Division of Infectious Diseases, Houston Methodist Hospital, Houston, TX, USA., Monogue ML; University of Texas Southwestern Medical Center, Dallas, TX, USA., Moore WJ; Department of Antimicrobial Stewardship, Northwestern Medicine, Chicago, IL, USA., Olson S; Sinai-Grace Hospital Detroit Medical Center, Detroit, MI, USA., Oxer J; Division of Infectious Diseases, Weill Cornell Medicine, New York, NY, USA., Pearson JC; Department of Pharmacy, Brigham and Women's Hospital, Boston, MA, USA., Pham C; Division of Infectious Diseases, Department of Medicine, and Department of Pharmaceutical Services, University of California, Los Angeles, CA, USA., Pinargote P; Ochsner Louisiana State University Health, Shreveport, LA, USA., Polk C; Atrium Health, Charlotte, NC, USA., Satlin MJ; Division of Infectious Diseases, Weill Cornell Medicine, New York, NY, USA., Satola SW; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA., Shah S; University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Tamma PD; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Tran TT; Division of Infectious Diseases, Houston Methodist Hospital, Houston, TX, USA., van Duin D; Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC, USA., VanNatta M; Ochsner Louisiana State University Health, Shreveport, LA, USA., Vega A; Department of Pharmacy and Antimicrobial Stewardship, Jackson Memorial Hospital, Miami, FL, USA., Venugopalan V; University of Florida College of Pharmacy, Gainesville, FL, USA., Veve MP; Department of Pharmacy, Henry Ford Hospital, Detroit, MI, USA; Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA., Wangchinda W; University of Michigan College of Pharmacy, Ann Arbor, MI, USA., Witt LS; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA., Wu JY; Department of Pharmacy, Cleveland Clinic, Cleveland, OH, USA., Pogue JM; University of Michigan College of Pharmacy, Ann Arbor, MI, USA.
Corporate Authors: PRECEDENT Network
Source: The Lancet. Infectious diseases [Lancet Infect Dis] 2025 May; Vol. 25 (5), pp. 574-584. Date of Electronic Publication: 2024 Dec 16.
Publication Type: Journal Article; Multicenter Study; Observational Study; Comparative Study
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effectiveness of ceftazidime-avibactam versus ceftolozane-tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the USA (CACTUS): a multicentre, retrospective, observational study.
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