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PAX5::AUTS2 childhood B-ALL: a relapse-prone genetic subtype with frequent central nervous system involvement and a poor outcome.

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Title: PAX5::AUTS2 childhood B-ALL: a relapse-prone genetic subtype with frequent central nervous system involvement and a poor outcome.
Authors: Caye-Eude A; Department of Genetics, University Hospital Robert Debré, Paris, France.; INSERM UMR_S1131, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France., Fazio G; Tettamanti Center, Fondazione IRCCS, San Gerardo dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Pastorczak A; Department of Genetic Predisposition to Cancer, Medical University of Łódź, Łódź, Poland., Boer JM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Steinemann D; Department of Human Genetics, Hannover Medical School, Hannover, Germany., Ganguli D; Administrative-Lead Genomics, Tata Translational Cancer Research Center/Tata Medical Center, Kolkata, India., Sonneveld E; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Dutch Childhood Oncology Group (DCOG), Utrecht, The Netherlands., Haslinger S; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; Labdia Labordiagnostik, Vienna, Austria., D'Andrea L; Department of Pediatric Hematology and Oncology, Hospital Pereira Rossell, Pérez Scremini Foundation, Montevideo, Uruguay., Bradtke J; Universitätsklinikum Gießen und Marburg, Institut für Pathologie, Onkogenetisches Labor Molekularpathologie, Gießen, Germany., Lopes BA; Leukemia DataLab, Instituto Nacional de Câncer-INCA, Rio de Janeiro, Brazil., Zaliova M; CLIP (Childhood Leukaemia Investigation Prague), Prague, Czech Republic.; Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; University Hospital Motol, Prague, Czech Republic., Escherich G; University Medical Center Hamburg-Eppendorf, Hamburg, Germany., König M; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; Labdia Labordiagnostik, Vienna, Austria., Fortschegger K; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria., Inthal A; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; Labdia Labordiagnostik, Vienna, Austria., Stasevich I; NHS North Thames Genomic Laboratory Hub, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Emerenciano M; Genetics of Acute Leukaemia Laboratory-GenLAb, Instituto Nacional de Câncer-INCA, Rio de Janeiro, Brazil., Trka J; CLIP (Childhood Leukaemia Investigation Prague), Prague, Czech Republic.; Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; University Hospital Motol, Prague, Czech Republic., Castillo L; Department of Pediatric Hematology and Oncology, Hospital Pereira Rossell, Pérez Scremini Foundation, Montevideo, Uruguay., Parihar M; Department of Laboratory Haematology and Cytogenetics, Tata Medical Centre, Kolkata, India., Moorman AV; Leukaemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK., Bergmann AK; Department of Human Genetics, Hannover Medical School, Hannover, Germany., den Boer ML; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Młynarski W; Department of Pediatrics, Oncology and Hematology, Medical University of Łódź, Łódź, Poland., Cazzaniga G; Tettamanti Center, Fondazione IRCCS, San Gerardo dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Cavé H; Department of Genetics, University Hospital Robert Debré, Paris, France.; INSERM UMR_S1131, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France., Nebral K; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; Labdia Labordiagnostik, Vienna, Austria., Schinnerl D; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria., Strehl S; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria. sabine.strehl@ccri.at.
Source: Leukemia [Leukemia] 2025 Feb; Vol. 39 (2), pp. 482-486. Date of Electronic Publication: 2024 Dec 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: PAX5::AUTS2 childhood B-ALL: a relapse-prone genetic subtype with frequent central nervous system involvement and a poor outcome.
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  Data: <searchLink fieldCode="AU" term="%22Caye-Eude+A%22">Caye-Eude A</searchLink>; Department of Genetics, University Hospital Robert Debré, Paris, France.; INSERM UMR_S1131, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Fazio+G%22">Fazio G</searchLink>; Tettamanti Center, Fondazione IRCCS, San Gerardo dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pastorczak+A%22">Pastorczak A</searchLink>; Department of Genetic Predisposition to Cancer, Medical University of Łódź, Łódź, Poland.<br /><searchLink fieldCode="AU" term="%22Boer+JM%22">Boer JM</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Steinemann+D%22">Steinemann D</searchLink>; Department of Human Genetics, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Ganguli+D%22">Ganguli D</searchLink>; Administrative-Lead Genomics, Tata Translational Cancer Research Center/Tata Medical Center, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Sonneveld+E%22">Sonneveld E</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Dutch Childhood Oncology Group (DCOG), Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Haslinger+S%22">Haslinger S</searchLink>; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; Labdia Labordiagnostik, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22D'Andrea+L%22">D'Andrea L</searchLink>; Department of Pediatric Hematology and Oncology, Hospital Pereira Rossell, Pérez Scremini Foundation, Montevideo, Uruguay.<br /><searchLink fieldCode="AU" term="%22Bradtke+J%22">Bradtke J</searchLink>; Universitätsklinikum Gießen und Marburg, Institut für Pathologie, Onkogenetisches Labor Molekularpathologie, Gießen, Germany.<br /><searchLink fieldCode="AU" term="%22Lopes+BA%22">Lopes BA</searchLink>; Leukemia DataLab, Instituto Nacional de Câncer-INCA, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Zaliova+M%22">Zaliova M</searchLink>; CLIP (Childhood Leukaemia Investigation Prague), Prague, Czech Republic.; Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; University Hospital Motol, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Escherich+G%22">Escherich G</searchLink>; University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22König+M%22">König M</searchLink>; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; Labdia Labordiagnostik, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Fortschegger+K%22">Fortschegger K</searchLink>; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Inthal+A%22">Inthal A</searchLink>; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; Labdia Labordiagnostik, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Stasevich+I%22">Stasevich I</searchLink>; NHS North Thames Genomic Laboratory Hub, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Emerenciano+M%22">Emerenciano M</searchLink>; Genetics of Acute Leukaemia Laboratory-GenLAb, Instituto Nacional de Câncer-INCA, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Trka+J%22">Trka J</searchLink>; CLIP (Childhood Leukaemia Investigation Prague), Prague, Czech Republic.; Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; University Hospital Motol, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Castillo+L%22">Castillo L</searchLink>; Department of Pediatric Hematology and Oncology, Hospital Pereira Rossell, Pérez Scremini Foundation, Montevideo, Uruguay.<br /><searchLink fieldCode="AU" term="%22Parihar+M%22">Parihar M</searchLink>; Department of Laboratory Haematology and Cytogenetics, Tata Medical Centre, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Moorman+AV%22">Moorman AV</searchLink>; Leukaemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Bergmann+AK%22">Bergmann AK</searchLink>; Department of Human Genetics, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22den+Boer+ML%22">den Boer ML</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Młynarski+W%22">Młynarski W</searchLink>; Department of Pediatrics, Oncology and Hematology, Medical University of Łódź, Łódź, Poland.<br /><searchLink fieldCode="AU" term="%22Cazzaniga+G%22">Cazzaniga G</searchLink>; Tettamanti Center, Fondazione IRCCS, San Gerardo dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cavé+H%22">Cavé H</searchLink>; Department of Genetics, University Hospital Robert Debré, Paris, France.; INSERM UMR_S1131, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Nebral+K%22">Nebral K</searchLink>; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; Labdia Labordiagnostik, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Schinnerl+D%22">Schinnerl D</searchLink>; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Strehl+S%22">Strehl S</searchLink>; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria. sabine.strehl@ccri.at.
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  Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2025 Feb; Vol. 39 (2), pp. 482-486. <i>Date of Electronic Publication: </i>2024 Dec 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%2C+Specialist+Journals%22">Nature Publishing Group, Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8704895 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208876924%22">08876924 </searchLink><i>NLM ISO Abbreviation: </i>Leukemia <i>Subsets: </i>MEDLINE; In Process
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