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CSF1-R inhibition attenuates posttraumatic osteoarthritis and quadriceps atrophy following ligament injury.

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Title: CSF1-R inhibition attenuates posttraumatic osteoarthritis and quadriceps atrophy following ligament injury.
Authors: Keeble AR; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY, USA., Thomas NT; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, KY, USA., Balawender PJ; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA., Brightwell CR; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, KY, USA., Gonzalez-Velez S; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY, USA., O'Daniel MG; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA., Conley CE; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA., Stone AV; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA., Johnson DL; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA., Noehren B; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, KY, USA., Jacobs CA; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.; Mass General Brigham Sports Medicine, Harvard Medical School, Boston, MA, USA., Fry CS; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, KY, USA., Owen AM; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, KY, USA.
Source: The Journal of physiology [J Physiol] 2025 Dec; Vol. 603 (23), pp. 7549-7566. Date of Electronic Publication: 2024 Dec 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CSF1-R inhibition attenuates posttraumatic osteoarthritis and quadriceps atrophy following ligament injury.
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  Data: <searchLink fieldCode="AU" term="%22Keeble+AR%22">Keeble AR</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+NT%22">Thomas NT</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Balawender+PJ%22">Balawender PJ</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Brightwell+CR%22">Brightwell CR</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Velez+S%22">Gonzalez-Velez S</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22O'Daniel+MG%22">O'Daniel MG</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Conley+CE%22">Conley CE</searchLink>; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Stone+AV%22">Stone AV</searchLink>; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+DL%22">Johnson DL</searchLink>; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Noehren+B%22">Noehren B</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Jacobs+CA%22">Jacobs CA</searchLink>; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.; Mass General Brigham Sports Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fry+CS%22">Fry CS</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Owen+AM%22">Owen AM</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, KY, USA.
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  Data: <searchLink fieldCode="JN" term="%220266262%22">The Journal of physiology</searchLink> [J Physiol] 2025 Dec; Vol. 603 (23), pp. 7549-7566. <i>Date of Electronic Publication: </i>2024 Dec 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cambridge+Univ%2E+Press%22">Cambridge Univ. Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0266262 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1469-7793 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223751%22">00223751 </searchLink><i>NLM ISO Abbreviation: </i>J Physiol <i>Subsets: </i>MEDLINE
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        Value: 10.1113/JP286815
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              M: 12
              Text: 2025 Dec
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