An exploratory study of the safety profile and neurocognitive function after single doses of mitragynine in humans.

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Title: An exploratory study of the safety profile and neurocognitive function after single doses of mitragynine in humans.
Authors: Prevete E; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands.; Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, Rome, 00185, Italy., Theunissen EL; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands., Kuypers KPC; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands., Paci R; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands., Reckweg JT; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands., Cavarra M; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands., Toennes SW; Institute of Legal Medicine, University Hospital, Goethe University, Frankfurt/Main, Germany., Ritscher S; Institute of Legal Medicine, University Hospital, Goethe University, Frankfurt/Main, Germany., Bersani G; Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Corso della Repubblica 79, Latina, 04100, Italy., Corazza O; Department of Clinical, Pharmacological and Biological Sciences, College Lane, University of Hertfordshire, Hatfield, AL10 9AB, UK.; Department of Psychology and Cognitive Science, University of Trento, Corso Bettini, 84, Rovereto, 38068, Italy., Pasquini M; Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, Rome, 00185, Italy., Ramaekers JG; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands. j.ramaekers@maastrichtuniversity.nl.
Source: Psychopharmacology [Psychopharmacology (Berl)] 2025 Jun; Vol. 242 (6), pp. 1363-1376. Date of Electronic Publication: 2024 Dec 26.
Publication Type: Clinical Trial, Phase I; Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-2072
DOI:10.1007/s00213-024-06734-2