A conserved pilin from uncultured gut bacterial clade TANB77 enhances cancer immunotherapy.

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Title: A conserved pilin from uncultured gut bacterial clade TANB77 enhances cancer immunotherapy.
Authors: Kim CY; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.; Brain Korea 21 (BK21) FOUR Program, Yonsei Education & Research Center for Biosystems, Yonsei University, Seoul, 03722, Republic of Korea.; European Molecular Biology Laboratory, Molecular Systems Biology Unit, 69117, Heidelberg, Germany., Park DJ; Brain Korea 21 (BK21) FOUR Program, Yonsei Education & Research Center for Biosystems, Yonsei University, Seoul, 03722, Republic of Korea.; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea., Ahn BC; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.; Center for Lung Cancer, Division of Hematology and Oncology, Department of Internal Medicine, Research Institute and Hospital, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea., Baek S; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.; Brain Korea 21 (BK21) FOUR Program, Yonsei Education & Research Center for Biosystems, Yonsei University, Seoul, 03722, Republic of Korea., Hong MH; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea., Nguyen LT; Department of Nano-bioengineering, Incheon National University, Incheon, 22012, Republic of Korea., Hwang SH; Department of Nano-bioengineering, Incheon National University, Incheon, 22012, Republic of Korea., Kim N; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.; Brain Korea 21 (BK21) FOUR Program, Yonsei Education & Research Center for Biosystems, Yonsei University, Seoul, 03722, Republic of Korea., Podlesny D; European Molecular Biology Laboratory, Molecular Systems Biology Unit, 69117, Heidelberg, Germany., Orakov A; European Molecular Biology Laboratory, Molecular Systems Biology Unit, 69117, Heidelberg, Germany., Schudoma C; European Molecular Biology Laboratory, Molecular Systems Biology Unit, 69117, Heidelberg, Germany., Robbani SM; European Molecular Biology Laboratory, Molecular Systems Biology Unit, 69117, Heidelberg, Germany., Shim HS; Department of Pathology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea., Yoon HI; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea., Lee CY; Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea., Park SY; Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.; Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Yong D; Department of Laboratory Medicine, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea., Han M; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea., Bork P; European Molecular Biology Laboratory, Molecular Systems Biology Unit, 69117, Heidelberg, Germany., Kim BC; Department of Nano-bioengineering, Incheon National University, Incheon, 22012, Republic of Korea. introbc@gmail.com., Ha SJ; Brain Korea 21 (BK21) FOUR Program, Yonsei Education & Research Center for Biosystems, Yonsei University, Seoul, 03722, Republic of Korea. sjha@yonsei.ac.kr.; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. sjha@yonsei.ac.kr.; POSTECH Biotech Center, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea. sjha@yonsei.ac.kr., Kim HR; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea. nobelg@yuhs.ac., Lee I; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. insuklee@yonsei.ac.kr.; Brain Korea 21 (BK21) FOUR Program, Yonsei Education & Research Center for Biosystems, Yonsei University, Seoul, 03722, Republic of Korea. insuklee@yonsei.ac.kr.; POSTECH Biotech Center, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea. insuklee@yonsei.ac.kr.
Source: Nature communications [Nat Commun] 2024 Dec 27; Vol. 15 (1), pp. 10726. Date of Electronic Publication: 2024 Dec 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-024-55388-3