The molecular bacterial load assay predicts treatment responses in patients with pre-XDR/XDR-tuberculosis more accurately than GeneXpert Ultra MTB/Rif.

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Title: The molecular bacterial load assay predicts treatment responses in patients with pre-XDR/XDR-tuberculosis more accurately than GeneXpert Ultra MTB/Rif.
Authors: Neumann M; Division of Infection Immunology, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany., Reimann M; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; Respiratory Medicine & International Health, University of Lübeck, Lübeck, Germany., Chesov D; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; Nicolae Testemitanu State University of Medicine and Pharmacy, Stefan cel Mare si Sfant Boulevard 165, MD-2004 Chisinau, Republic of Moldova., Popa C; National Institute of Pneumology Marius Nasta, Șoseaua Viilor 90, 050159 Bucharest, Romania., Dragomir A; National Institute of Pneumology Marius Nasta, Șoseaua Viilor 90, 050159 Bucharest, Romania., Popescu O; National Institute of Pneumology Marius Nasta, Șoseaua Viilor 90, 050159 Bucharest, Romania., Munteanu R; National Institute of Pneumology Marius Nasta, Șoseaua Viilor 90, 050159 Bucharest, Romania., Hölscher A; Division of Infection Immunology, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany., Honeyborne I; Centre for Clinical Microbiology, University College London, Gower Street, London WC1E 6BT, United Kingdom., Heyckendorf J; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; Internal Medicine I, University Hospitals Schleswig-Holstein, Kiel, Germany; Pulmonology and Inflammatory Medicine, Christian Albrechts-University, Kiel, Germany., Lange C; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; Respiratory Medicine & International Health, University of Lübeck, Lübeck, Germany; Baylor College of Medicine and Texas Children´s Hospital, Houston, TX, USA., Hölscher C; Division of Infection Immunology, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany. Electronic address: choelscher@fz-borstel.de., Kalsdorf B; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany.
Source: The Journal of infection [J Infect] 2025 Feb; Vol. 90 (2), pp. 106399. Date of Electronic Publication: 2024 Dec 27.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: W.B. Saunders Country of Publication: England NLM ID: 7908424 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2742 (Electronic) Linking ISSN: 01634453 NLM ISO Abbreviation: J Infect Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The molecular bacterial load assay predicts treatment responses in patients with pre-XDR/XDR-tuberculosis more accurately than GeneXpert Ultra MTB/Rif.
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  Data: <searchLink fieldCode="AU" term="%22Neumann+M%22">Neumann M</searchLink>; Division of Infection Immunology, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany.<br /><searchLink fieldCode="AU" term="%22Reimann+M%22">Reimann M</searchLink>; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; Respiratory Medicine & International Health, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Chesov+D%22">Chesov D</searchLink>; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; Nicolae Testemitanu State University of Medicine and Pharmacy, Stefan cel Mare si Sfant Boulevard 165, MD-2004 Chisinau, Republic of Moldova.<br /><searchLink fieldCode="AU" term="%22Popa+C%22">Popa C</searchLink>; National Institute of Pneumology Marius Nasta, Șoseaua Viilor 90, 050159 Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Dragomir+A%22">Dragomir A</searchLink>; National Institute of Pneumology Marius Nasta, Șoseaua Viilor 90, 050159 Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Popescu+O%22">Popescu O</searchLink>; National Institute of Pneumology Marius Nasta, Șoseaua Viilor 90, 050159 Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Munteanu+R%22">Munteanu R</searchLink>; National Institute of Pneumology Marius Nasta, Șoseaua Viilor 90, 050159 Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Hölscher+A%22">Hölscher A</searchLink>; Division of Infection Immunology, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany.<br /><searchLink fieldCode="AU" term="%22Honeyborne+I%22">Honeyborne I</searchLink>; Centre for Clinical Microbiology, University College London, Gower Street, London WC1E 6BT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Heyckendorf+J%22">Heyckendorf J</searchLink>; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; Internal Medicine I, University Hospitals Schleswig-Holstein, Kiel, Germany; Pulmonology and Inflammatory Medicine, Christian Albrechts-University, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Lange+C%22">Lange C</searchLink>; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; Respiratory Medicine & International Health, University of Lübeck, Lübeck, Germany; Baylor College of Medicine and Texas Children´s Hospital, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Hölscher+C%22">Hölscher C</searchLink>; Division of Infection Immunology, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany. Electronic address: choelscher@fz-borstel.de.<br /><searchLink fieldCode="AU" term="%22Kalsdorf+B%22">Kalsdorf B</searchLink>; German Center for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany.
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  Data: <searchLink fieldCode="JN" term="%227908424%22">The Journal of infection</searchLink> [J Infect] 2025 Feb; Vol. 90 (2), pp. 106399. <i>Date of Electronic Publication: </i>2024 Dec 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders%22">W.B. Saunders </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7908424 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-2742 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201634453%22">01634453 </searchLink><i>NLM ISO Abbreviation: </i>J Infect <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jinf.2024.106399
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