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DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells.

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Title: DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells.
Authors: Shi X; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA.; School of Life Sciences, Tsinghua University, Beijing, China., Li Y; Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Shanghai, China., Zhou H; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA., Hou X; Department of Thyroid and Neck Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China., Yang J; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA., Malik V; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA., Faiola F; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ding J; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bao X; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China., Modic M; The Francis Crick Institute and University College London, London, UK., Zhang W; College of Life Sciences, Nankai University, Tianjin, China., Chen L; College of Life Sciences, Nankai University, Tianjin, China., Mahmood SR; Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Apostolou E; Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Yang FC; Department of Molecular Medicine/Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Xu M; Department of Molecular Medicine/Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Xie W; School of Life Sciences, Tsinghua University, Beijing, China., Huang X; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA., Chen Y; Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China. yongchen@sibcb.ac.cn., Wang J; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA. jw3925@cumc.columbia.edu.
Source: Nature communications [Nat Commun] 2024 Dec 30; Vol. 15 (1), pp. 10803. Date of Electronic Publication: 2024 Dec 30.
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells.
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  Data: <searchLink fieldCode="AU" term="%22Shi+X%22">Shi X</searchLink>; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA.; School of Life Sciences, Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hou+X%22">Hou X</searchLink>; Department of Thyroid and Neck Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Malik+V%22">Malik V</searchLink>; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Faiola+F%22">Faiola F</searchLink>; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ding+J%22">Ding J</searchLink>; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bao+X%22">Bao X</searchLink>; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Modic+M%22">Modic M</searchLink>; The Francis Crick Institute and University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; College of Life Sciences, Nankai University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; College of Life Sciences, Nankai University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Mahmood+SR%22">Mahmood SR</searchLink>; Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Apostolou+E%22">Apostolou E</searchLink>; Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Yang+FC%22">Yang FC</searchLink>; Department of Molecular Medicine/Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Xu+M%22">Xu M</searchLink>; Department of Molecular Medicine/Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Xie+W%22">Xie W</searchLink>; School of Life Sciences, Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Huang+X%22">Huang X</searchLink>; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China. yongchen@sibcb.ac.cn.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA. jw3925@cumc.columbia.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Dec 30; Vol. 15 (1), pp. 10803. <i>Date of Electronic Publication: </i>2024 Dec 30.
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