Physiologically Based Pharmacokinetic Modeling and Simulation to Support a Change in the FDA-Labeled Dosing Frequency of RHB-105 Low-Dose Rifabutin Triple Therapy for Helicobacter pylori Eradication.
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| Title: | Physiologically Based Pharmacokinetic Modeling and Simulation to Support a Change in the FDA-Labeled Dosing Frequency of RHB-105 Low-Dose Rifabutin Triple Therapy for Helicobacter pylori Eradication. |
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| Authors: | Vakil N; School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Howden CW; College of Medicine, University of Tennessee, Memphis, TN, USA., Shah SC; Division of Gastroenterology, University of California, San Diego, CA, USA., Chen KF; Certara, Simcyp Division, Sheffield, UK., Offman E; Certara, Integrated Drug Development, Montreal, Quebec, Canada., Almenoff JS; RedHill Biopharma, Medical Affairs, Raleigh, NC, USA., Sheldon KL; RedHill Biopharma, Medical Affairs, Raleigh, NC, USA. |
| Source: | Journal of clinical pharmacology [J Clin Pharmacol] 2025 Jun; Vol. 65 (6), pp. 779-786. Date of Electronic Publication: 2025 Jan 02. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1552-4604 |
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| DOI: | 10.1002/jcph.6178 |