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Molecular and spatial analysis of tertiary lymphoid structures in Sjogren's syndrome.

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Title: Molecular and spatial analysis of tertiary lymphoid structures in Sjogren's syndrome.
Authors: Nayar S; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.; Birmingham Tissue Analytics, College of Medicine & Health, University of Birmingham, Birmingham, UK., Turner JD; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK., Asam S; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; UCL Genomics, Zayed Centre for Research into Rare Disease in Children, University College London, London, UK., Fennell E; School of Medicine & HRI & Bernal Institute, University of Limerick, Limerick, Ireland., Pugh M; Department of Immunology and Immunotherapy, College of Medicine & Health, University of Birmingham, Birmingham, UK., Colafrancesco S; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Berardicurti O; Rheumatology, Immunology and Clinical Medicine Unit, Department of Medicine, Università Campus Bio-Medico, Rome, and Immunorheumatology Unit, Fondazione Policlinico Universitario Campus Bio Medico, Rome, Italy., Smith CG; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK., Flint J; Birmingham Tissue Analytics, College of Medicine & Health, University of Birmingham, Birmingham, UK., Teodosio A; Birmingham Tissue Analytics, College of Medicine & Health, University of Birmingham, Birmingham, UK., Iannizzotto V; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK., Gardner DH; Birmingham Tissue Analytics, College of Medicine & Health, University of Birmingham, Birmingham, UK., van Roon J; Department of Rheumatology & Clinical Immunology/Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands., Korsunsky I; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA., Howdle D; Birmingham Tissue Analytics, College of Medicine & Health, University of Birmingham, Birmingham, UK., Frei AP; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Lassen KG; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Bowman SJ; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Ng WF; HRB Clinical Research Facility, University College Cork, Cork, Ireland., Croft AP; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK., Filer A; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.; Birmingham Tissue Analytics, College of Medicine & Health, University of Birmingham, Birmingham, UK., Fisher BA; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Buckley CD; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Barone F; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK. Fbarone@candeltx.com.; Candel Therapeutics, Needham, MA, USA. Fbarone@candeltx.com.
Corporate Authors: Roche Fibroblast Network Consortium
Source: Nature communications [Nat Commun] 2025 Jan 02; Vol. 16 (1), pp. 5. Date of Electronic Publication: 2025 Jan 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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Hoffmann-La Roche Ltd, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bowman+SJ%22">Bowman SJ</searchLink>; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Ng+WF%22">Ng WF</searchLink>; HRB Clinical Research Facility, University College Cork, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Croft+AP%22">Croft AP</searchLink>; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Filer+A%22">Filer A</searchLink>; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.; Birmingham Tissue Analytics, College of Medicine & Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Fisher+BA%22">Fisher BA</searchLink>; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Buckley+CD%22">Buckley CD</searchLink>; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK.; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Barone+F%22">Barone F</searchLink>; Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK. Fbarone@candeltx.com.; Candel Therapeutics, Needham, MA, USA. Fbarone@candeltx.com.
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