An ultra-conserved poison exon in the Tra2b gene encoding a splicing activator is essential for male fertility and meiotic cell division.
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| Title: | An ultra-conserved poison exon in the Tra2b gene encoding a splicing activator is essential for male fertility and meiotic cell division. |
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| Authors: | Dalgliesh C; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK.; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, NE1 3BZ, UK., Aldalaqan S; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK.; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, NE1 3BZ, UK., Atallah C; Bioinformatics Support Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Best A; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK., Scott E; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK.; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, NE1 3BZ, UK., Ehrmann I; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK.; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, NE1 3BZ, UK., Merces G; Newcastle University Biosciences Institute (NUBI), Innovation, Methodology and Application (IMA) Research Theme, Faculty of Medical Sciences, Newcastle University, NE2 4HH, Newcastle upon Tyne, UK.; Image Analysis Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Mannion J; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK., Badurova B; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK., Sandher R; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK., Illing Y; University of Cologne, Institute of Human Genetics, Kerpener Str. 34, 50931, Cologne, Germany., Wirth B; University of Cologne, Institute of Human Genetics, Kerpener Str. 34, 50931, Cologne, Germany.; Center for Molecular Genetics, University of Cologne, Cologne, Germany.; Center for Rare Diseases Cologne, University of Cologne, Cologne, Germany., Wells S; The Mary Lyon Centre at MRC Harwell, Harwell Campus, Oxfordshire, OX11 0RD, UK., Codner G; The Mary Lyon Centre at MRC Harwell, Harwell Campus, Oxfordshire, OX11 0RD, UK., Teboul L; The Mary Lyon Centre at MRC Harwell, Harwell Campus, Oxfordshire, OX11 0RD, UK., Smith GR; Bioinformatics Support Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Hedley A; Bioinformatics Support Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Herbert M; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK., de Rooij DG; Reproductive Biology Group, Division of Developmental Biology, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.; Center for Reproductive Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Miles C; Newcastle University Translational and Clinical Research Institute, Newcastle, NE1 3BZ, UK., Reynard LN; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK., Elliott DJ; Newcastle University Biosciences Institute (NUBI), Central Parkway, Newcastle University, NE1 3BZ, Newcastle upon Tyne, UK. david.elliott@ncl.ac.uk.; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, NE1 3BZ, UK. david.elliott@ncl.ac.uk. |
| Source: | The EMBO journal [EMBO J] 2025 Feb; Vol. 44 (3), pp. 877-902. Date of Electronic Publication: 2025 Jan 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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