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Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus.

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Title: Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus.
Authors: O'Keeffe M; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Booker SA; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Walsh D; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Li M; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Henley C; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Simões de Oliveira L; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Liu M; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Wang X; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Banqueri M; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Ridley K; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Dissanayake KN; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Martinez-Gonzalez C; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Craigie KJ; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Vasoya D; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Leah T; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., He X; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Hume DA; Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia., Duguid I; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Nolan MF; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Qiu J; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Wyllie DJA; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Dando OR; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Gonzalez-Sulser A; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Gan J; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK., Pridans C; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK.; Centre for Inflammation Research, The Queen's Medical Research Institute, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK., Kind PC; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK. pkind@exseed.ed.ac.uk.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK. pkind@exseed.ed.ac.uk., Hardingham GE; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK. Giles.Hardingham@ed.ac.uk.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK. Giles.Hardingham@ed.ac.uk.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK. Giles.Hardingham@ed.ac.uk.
Source: Nature neuroscience [Nat Neurosci] 2025 Feb; Vol. 28 (2), pp. 268-279. Date of Electronic Publication: 2025 Jan 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE
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Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Duguid+I%22">Duguid I</searchLink>; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Nolan+MF%22">Nolan MF</searchLink>; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Qiu+J%22">Qiu J</searchLink>; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Wyllie+DJA%22">Wyllie DJA</searchLink>; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; 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Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK.; Centre for Inflammation Research, The Queen's Medical Research Institute, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Kind+PC%22">Kind PC</searchLink>; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK. pkind@exseed.ed.ac.uk.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK. pkind@exseed.ed.ac.uk.<br /><searchLink fieldCode="AU" term="%22Hardingham+GE%22">Hardingham GE</searchLink>; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK. Giles.Hardingham@ed.ac.uk.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK. Giles.Hardingham@ed.ac.uk.; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK. Giles.Hardingham@ed.ac.uk.
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