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A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques.

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Title: A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques.
Authors: Zumbrun EE; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Garvey CB; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Wells JB; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Lynn GC; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Van Tongeren SA; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Steffens JT; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Wetzel KS; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Wetzel DL; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Esham HL; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Garza NL; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Lee ED; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Scruggs JL; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Rossi FD; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Brown ES; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Weidner JM; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Gomba LM; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., O'Brien KA; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Jay AN; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Zeng X; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Akers KS; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Kallgren PA; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Englund E; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Meinig JM; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Kugelman JR; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Moore JL; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Bloomfield HA; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Norris SL; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Bryan T; PharPoint Research, Inc., Wilmington, NC 28401, USA., Scheuerell CH; Labcorp Early Development Laboratories, Madison, WI 53704, USA., Walters J; Labcorp Early Development Laboratories, Madison, WI 53704, USA., Mollova N; Gilead Sciences, Inc., Foster City, CA 94404, USA., Blair C; Gilead Sciences, Inc., Foster City, CA 94404, USA., Babusis D; Gilead Sciences, Inc., Foster City, CA 94404, USA., Cihlar T; Gilead Sciences, Inc., Foster City, CA 94404, USA., Porter DP; Gilead Sciences, Inc., Foster City, CA 94404, USA., Singh B; Gilead Sciences, Inc., Foster City, CA 94404, USA., Hedskog C; Gilead Sciences, Inc., Foster City, CA 94404, USA., Bavari S; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Warren TK; United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; Geneva Foundation, Tacoma, WA 98402, USA., Bannister R; Gilead Sciences, Inc., Foster City, CA 94404, USA.
Source: Viruses [Viruses] 2024 Dec 18; Vol. 16 (12). Date of Electronic Publication: 2024 Dec 18.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques.
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