Pharmacokinetics and pharmacodynamics of an innovative psychedelic N,N-dimethyltryptamine/harmine formulation in healthy participants: a randomized controlled trial.
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| Title: | Pharmacokinetics and pharmacodynamics of an innovative psychedelic N,N-dimethyltryptamine/harmine formulation in healthy participants: a randomized controlled trial. |
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| Authors: | Mueller MJ; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Department of Health Science & Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland., Aicher HD; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.; Department of Psychology, University of Zurich, Zurich, Switzerland., Dornbierer DA; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.; Department of Forensic Pharmacology and Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland., Marten L; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland., Suay D; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; IMT School for Advanced Studies, Luca, Italy., Meling D; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Department of Psychosomatic Medicine and Psychotherapy, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany., Elsner C; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Wicki IA; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Müller J; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Poetzsch SN; Department of Forensic Pharmacology and Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland., Caflisch L; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Hempe A; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Faculty of Psychology, TU Dresden, Dresden, Germany., Steinhart CP; Institute of Neuroinformatics, University of Zurich, Zurich, Switzerland., Puchkov M; Institute of Pharmaceutical Technology, University of Basel, Basel, Switzerland., Kost J; Institute of Pharmaceutical Technology, University of Basel, Basel, Switzerland., Landolt HP; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Seifritz E; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland., Quednow BB; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Scheidegger M; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland. |
| Source: | The international journal of neuropsychopharmacology [Int J Neuropsychopharmacol] 2024 Dec 28; Vol. 28 (1). |
| Publication Type: | Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9815893 Publication Model: Print Cited Medium: Internet ISSN: 1469-5111 (Electronic) Linking ISSN: 14611457 NLM ISO Abbreviation: Int J Neuropsychopharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39774840 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Pharmacokinetics and pharmacodynamics of an innovative psychedelic N,N-dimethyltryptamine/harmine formulation in healthy participants: a randomized controlled trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Mueller+MJ%22">Mueller MJ</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Department of Health Science & Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Aicher+HD%22">Aicher HD</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.; Department of Psychology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dornbierer+DA%22">Dornbierer DA</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.; Department of Forensic Pharmacology and Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Marten+L%22">Marten L</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Suay+D%22">Suay D</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; IMT School for Advanced Studies, Luca, Italy.<br /><searchLink fieldCode="AU" term="%22Meling+D%22">Meling D</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Department of Psychosomatic Medicine and Psychotherapy, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Elsner+C%22">Elsner C</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wicki+IA%22">Wicki IA</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Müller+J%22">Müller J</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Poetzsch+SN%22">Poetzsch SN</searchLink>; Department of Forensic Pharmacology and Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Caflisch+L%22">Caflisch L</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hempe+A%22">Hempe A</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Faculty of Psychology, TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Steinhart+CP%22">Steinhart CP</searchLink>; Institute of Neuroinformatics, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Puchkov+M%22">Puchkov M</searchLink>; Institute of Pharmaceutical Technology, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kost+J%22">Kost J</searchLink>; Institute of Pharmaceutical Technology, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Landolt+HP%22">Landolt HP</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Seifritz+E%22">Seifritz E</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Quednow+BB%22">Quednow BB</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Scheidegger+M%22">Scheidegger M</searchLink>; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229815893%22">The international journal of neuropsychopharmacology</searchLink> [Int J Neuropsychopharmacol] 2024 Dec 28; Vol. 28 (1). – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9815893 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1469-5111 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214611457%22">14611457 </searchLink><i>NLM ISO Abbreviation: </i>Int J Neuropsychopharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39774840 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/ijnp/pyaf001 Languages: – Code: eng Text: English Titles: – TitleFull: Pharmacokinetics and pharmacodynamics of an innovative psychedelic N,N-dimethyltryptamine/harmine formulation in healthy participants: a randomized controlled trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mueller MJ – PersonEntity: Name: NameFull: Aicher HD – PersonEntity: Name: NameFull: Dornbierer DA – PersonEntity: Name: NameFull: Marten L – PersonEntity: Name: NameFull: Suay D – PersonEntity: Name: NameFull: Meling D – PersonEntity: Name: NameFull: Elsner C – PersonEntity: Name: NameFull: Wicki IA – PersonEntity: Name: NameFull: Müller J – PersonEntity: Name: NameFull: Poetzsch SN – PersonEntity: Name: NameFull: Caflisch L – PersonEntity: Name: NameFull: Hempe A – PersonEntity: Name: NameFull: Steinhart CP – PersonEntity: Name: NameFull: Puchkov M – PersonEntity: Name: NameFull: Kost J – PersonEntity: Name: NameFull: Landolt HP – PersonEntity: Name: NameFull: Seifritz E – PersonEntity: Name: NameFull: Quednow BB – PersonEntity: Name: NameFull: Scheidegger M IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 12 Text: 2024 Dec 28 Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1469-5111 Numbering: – Type: volume Value: 28 – Type: issue Value: 1 Titles: – TitleFull: The international journal of neuropsychopharmacology Type: main |
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