Precursors of exhausted T cells are pre-emptively formed in acute infection. - Chu T; Wu M; Hoellbacher B; de Almeida GP; Wurmser C; Berner J; Donhauser LV; Gerullis AK; Lin S; Cepeda-Mayorga JD; Kilb II; Bongers L; et al. (Nature, 2025)