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α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia.

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Title: α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia.
Authors: Millman SE; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Chaves-Perez A; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Janaki-Raman S; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY., Ho YJ; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Morris JP 4th; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Narendra V; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Chen CC; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Jackson BT; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Yashinskie JJ; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Mezzadra R; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Devine TI; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Barthet VJA; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Saoi M; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY., Baslan T; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Tian S; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY., Sachs Z; Division of Hematology, Oncology, and Transplantation, Department of Medicine and Masonic Cancer Center, University of Minnesota, Minneapolis, MN., Finley LWS; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Cross JR; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY., Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.; Howard Hughes Medical Institute, Chevy Chase, MD.
Source: Blood [Blood] 2025 Mar 27; Vol. 145 (13), pp. 1422-1436.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Millman+SE%22">Millman SE</searchLink>; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Chaves-Perez+A%22">Chaves-Perez A</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Janaki-Raman+S%22">Janaki-Raman S</searchLink>; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Ho+YJ%22">Ho YJ</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Morris+JP+4th%22">Morris JP 4th</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Narendra+V%22">Narendra V</searchLink>; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Chen+CC%22">Chen CC</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Jackson+BT%22">Jackson BT</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Yashinskie+JJ%22">Yashinskie JJ</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Mezzadra+R%22">Mezzadra R</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Devine+TI%22">Devine TI</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Barthet+VJA%22">Barthet VJA</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Saoi+M%22">Saoi M</searchLink>; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Baslan+T%22">Baslan T</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Tian+S%22">Tian S</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Sachs+Z%22">Sachs Z</searchLink>; Division of Hematology, Oncology, and Transplantation, Department of Medicine and Masonic Cancer Center, University of Minnesota, Minneapolis, MN.<br /><searchLink fieldCode="AU" term="%22Finley+LWS%22">Finley LWS</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Cross+JR%22">Cross JR</searchLink>; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Lowe+SW%22">Lowe SW</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY.; Howard Hughes Medical Institute, Chevy Chase, MD.
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