Design, Structure-Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists.
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| Title: | Design, Structure-Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists. |
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| Authors: | Sawyer JR; Resolute Bio, 48 Dunham Rd., Suite 5400, Beverly, MA 01915, USA.; Department of Chemistry and Biochemistry, The University of Arizona, 1306 E. University Blvd, Tucson, AZ 85721, USA.; Peptide Scientia, 8 Nathan Stone Lane, Southborough, MA 01772, USA., Audie JA; Eudoxia Life Sciences, 520 Squire Hill Rd., Cheshire, CT 06410, USA., Swanson J; Eudoxia Life Sciences, 520 Squire Hill Rd., Cheshire, CT 06410, USA., Diller D; Eudoxia Life Sciences, 520 Squire Hill Rd., Cheshire, CT 06410, USA., Santiago S; Resolute Bio, 48 Dunham Rd., Suite 5400, Beverly, MA 01915, USA., Gribkoff VK; Resolute Bio, 48 Dunham Rd., Suite 5400, Beverly, MA 01915, USA., Ackerman A; Resolute Bio, 48 Dunham Rd., Suite 5400, Beverly, MA 01915, USA., Hruby VJ; Department of Chemistry and Biochemistry, The University of Arizona, 1306 E. University Blvd, Tucson, AZ 85721, USA., Gobbo G; XtalPi US, XtalPi Inc., 245 Main Street, Cambridge, MA 02142, USA., Bellucci MA; XtalPi US, XtalPi Inc., 245 Main Street, Cambridge, MA 02142, USA., Glauser WA; XtalPi US, XtalPi Inc., 245 Main Street, Cambridge, MA 02142, USA., Pentelute BL; Resolute Bio, 48 Dunham Rd., Suite 5400, Beverly, MA 01915, USA., Sawyer TK; Resolute Bio, 48 Dunham Rd., Suite 5400, Beverly, MA 01915, USA.; Maestro Therapeutics, 8 Nathan Stone Lane, Southborough, MA 01772, USA. |
| Source: | Molecules (Basel, Switzerland) [Molecules] 2024 Dec 24; Vol. 30 (1). Date of Electronic Publication: 2024 Dec 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1420-3049 |
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| DOI: | 10.3390/molecules30010012 |
