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Head-to-Head Comparison of Aptamer- and Antibody-Based Proteomic Platforms in Human Cerebrospinal Fluid Samples from a Real-World Memory Clinic Cohort.

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Title: Head-to-Head Comparison of Aptamer- and Antibody-Based Proteomic Platforms in Human Cerebrospinal Fluid Samples from a Real-World Memory Clinic Cohort.
Authors: Puerta R; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; PhD Program in Biotecnology, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain., Cano A; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., García-González P; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., García-Gutiérrez F; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain., Capdevila M; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Departament de Farmacologia, Toxicologia i Química Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 08007 Barcelona, Spain., de Rojas I; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., Olivé C; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain., Blázquez-Folch J; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain., Sotolongo-Grau O; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain., Miguel A; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain., Montrreal L; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain., Martino-Adami P; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany., Khan A; Janssen Pharmaceutica NV, a Johnson & Johnson Company, 2340 Beerse, Belgium., Orellana A; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., Sung YJ; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO 63108, USA.; Hope Center for Neurological Disorders, Washington University, St. Louis, MO 63110, USA., Frikke-Schmidt R; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark., Marchant N; Division of Psychiatry, University College London, London W1T 7NK, UK., Lambert JC; Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Université de Lille, F-59000 Lille, France.; Institut Pasteur de Lille, Inserm U1167, CHU de Lille, LabEx DISTALZ, Université de Lille, F-59000 Lille, France., Rosende-Roca M; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain., Alegret M; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., Fernández MV; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., Marquié M; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., Valero S; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., Tárraga L; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., Cruchaga C; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO 63108, USA.; Hope Center for Neurological Disorders, Washington University, St. Louis, MO 63110, USA., Ramírez A; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, Medical Faculty, University Hospital Bonn, 53127 Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Psychiatry and Glenn, Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX 78229, USA.; Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany., Boada M; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain., Smets B; Janssen Pharmaceutica NV, a Johnson & Johnson Company, 2340 Beerse, Belgium., Cabrera-Socorro A; Janssen Pharmaceutica NV, a Johnson & Johnson Company, 2340 Beerse, Belgium., Ruiz A; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX 77204, USA.
Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 31; Vol. 26 (1). Date of Electronic Publication: 2024 Dec 31.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Head-to-Head Comparison of Aptamer- and Antibody-Based Proteomic Platforms in Human Cerebrospinal Fluid Samples from a Real-World Memory Clinic Cohort.
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  Data: <searchLink fieldCode="AU" term="%22Puerta+R%22">Puerta R</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; PhD Program in Biotecnology, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cano+A%22">Cano A</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22García-González+P%22">García-González P</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22García-Gutiérrez+F%22">García-Gutiérrez F</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Capdevila+M%22">Capdevila M</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Departament de Farmacologia, Toxicologia i Química Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 08007 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22de+Rojas+I%22">de Rojas I</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Olivé+C%22">Olivé C</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Blázquez-Folch+J%22">Blázquez-Folch J</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Sotolongo-Grau+O%22">Sotolongo-Grau O</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Miguel+A%22">Miguel A</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Montrreal+L%22">Montrreal L</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Martino-Adami+P%22">Martino-Adami P</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Khan+A%22">Khan A</searchLink>; Janssen Pharmaceutica NV, a Johnson & Johnson Company, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Orellana+A%22">Orellana A</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sung+YJ%22">Sung YJ</searchLink>; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO 63108, USA.; Hope Center for Neurological Disorders, Washington University, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Frikke-Schmidt+R%22">Frikke-Schmidt R</searchLink>; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Marchant+N%22">Marchant N</searchLink>; Division of Psychiatry, University College London, London W1T 7NK, UK.<br /><searchLink fieldCode="AU" term="%22Lambert+JC%22">Lambert JC</searchLink>; Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Université de Lille, F-59000 Lille, France.; Institut Pasteur de Lille, Inserm U1167, CHU de Lille, LabEx DISTALZ, Université de Lille, F-59000 Lille, France.<br /><searchLink fieldCode="AU" term="%22Rosende-Roca+M%22">Rosende-Roca M</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Alegret+M%22">Alegret M</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández+MV%22">Fernández MV</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Marquié+M%22">Marquié M</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Valero+S%22">Valero S</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Tárraga+L%22">Tárraga L</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO 63108, USA.; Hope Center for Neurological Disorders, Washington University, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Ramírez+A%22">Ramírez A</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, Medical Faculty, University Hospital Bonn, 53127 Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Psychiatry and Glenn, Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX 78229, USA.; Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Boada+M%22">Boada M</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Smets+B%22">Smets B</searchLink>; Janssen Pharmaceutica NV, a Johnson & Johnson Company, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Cabrera-Socorro+A%22">Cabrera-Socorro A</searchLink>; Janssen Pharmaceutica NV, a Johnson & Johnson Company, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Ruiz+A%22">Ruiz A</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08029 Barcelona, Spain.; Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, 28029 Madrid, Spain.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX 77204, USA.
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