Sophaline B inhibits non-small cell lung cancer by activating NLRP3/caspase-1/GSDMD-dependent pyroptosis and PI3K/AKT/mTOR-mediated autophagy.
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| Title: | Sophaline B inhibits non-small cell lung cancer by activating NLRP3/caspase-1/GSDMD-dependent pyroptosis and PI3K/AKT/mTOR-mediated autophagy. |
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| Authors: | Hou Y; Institute of Biopharmaceutical and Health Engineering, State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Gene and Antibody Therapy, Shenzhen International Graduate School, Tsinghua University, Shenzhen, Guangdong, China., Wang Z; Department of Interventional, Shenzhen People's Hospital, Shenzhen, Guangdong, China., Wu Y; Department of Subject Service and Consultation, Jinan University Library, Guangdong Clinical Translational Center for Targeted Drug, Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong, China., Deng T; Institute of Biopharmaceutical and Health Engineering, State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Gene and Antibody Therapy, Shenzhen International Graduate School, Tsinghua University, Shenzhen, Guangdong, China., Yang S; Department of Subject Service and Consultation, Jinan University Library, Guangdong Clinical Translational Center for Targeted Drug, Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong, China., Ma S; Institute of Biopharmaceutical and Health Engineering, State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Gene and Antibody Therapy, Shenzhen International Graduate School, Tsinghua University, Shenzhen, Guangdong, China., Zhang Y; Department of Subject Service and Consultation, Jinan University Library, Guangdong Clinical Translational Center for Targeted Drug, Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong, China., Luo D; Department of Subject Service and Consultation, Jinan University Library, Guangdong Clinical Translational Center for Targeted Drug, Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong, China., Chen Y; Department of Subject Service and Consultation, Jinan University Library, Guangdong Clinical Translational Center for Targeted Drug, Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong, China., Dai X; Institute of Biopharmaceutical and Health Engineering, State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Gene and Antibody Therapy, Shenzhen International Graduate School, Tsinghua University, Shenzhen, Guangdong, China. |
| Source: | Natural product research [Nat Prod Res] 2026 Jun; Vol. 40 (11), pp. 3015-3027. Date of Electronic Publication: 2025 Jan 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1478-6427 |
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| DOI: | 10.1080/14786419.2024.2448839 |
