Microbiota transplant for hepatic encephalopathy in cirrhosis: The THEMATIC trial.

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Title: Microbiota transplant for hepatic encephalopathy in cirrhosis: The THEMATIC trial.
Authors: Bajaj JS; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA. Electronic address: jasmohan.bajaj@vcuhealth.org., Fagan A; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Gavis EA; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Sterling RK; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Gallagher ML; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Lee H; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Matherly SC; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Siddiqui MS; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Bartels A; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Mousel T; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Davis BC; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Puri P; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Fuchs M; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA., Moutsoglou DM; Gastroenterology, Minneapolis VA Medical Center, Minneapolis, Minnesota, USA; Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Thacker LR; Department of Biostatistics, Virginia Commonwealth University, Richmond, Virginia, USA., Sikaroodi M; Microbiome Analysis Center, George Mason University, Manassas, Virginia, USA., Gillevet PM; Microbiome Analysis Center, George Mason University, Manassas, Virginia, USA., Khoruts A; Division of Gastroenterology and Hepatology and Center for Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Source: Journal of hepatology [J Hepatol] 2025 Jul; Vol. 83 (1), pp. 81-91. Date of Electronic Publication: 2025 Jan 10.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Microbiota transplant for hepatic encephalopathy in cirrhosis: The THEMATIC trial.
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  Data: <searchLink fieldCode="AU" term="%22Bajaj+JS%22">Bajaj JS</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA. Electronic address: jasmohan.bajaj@vcuhealth.org.<br /><searchLink fieldCode="AU" term="%22Fagan+A%22">Fagan A</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Gavis+EA%22">Gavis EA</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Sterling+RK%22">Sterling RK</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Gallagher+ML%22">Gallagher ML</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Matherly+SC%22">Matherly SC</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Siddiqui+MS%22">Siddiqui MS</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Bartels+A%22">Bartels A</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Mousel+T%22">Mousel T</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Davis+BC%22">Davis BC</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Puri+P%22">Puri P</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Fuchs+M%22">Fuchs M</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Moutsoglou+DM%22">Moutsoglou DM</searchLink>; Gastroenterology, Minneapolis VA Medical Center, Minneapolis, Minnesota, USA; Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Thacker+LR%22">Thacker LR</searchLink>; Department of Biostatistics, Virginia Commonwealth University, Richmond, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Sikaroodi+M%22">Sikaroodi M</searchLink>; Microbiome Analysis Center, George Mason University, Manassas, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Gillevet+PM%22">Gillevet PM</searchLink>; Microbiome Analysis Center, George Mason University, Manassas, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Khoruts+A%22">Khoruts A</searchLink>; Division of Gastroenterology and Hepatology and Center for Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
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  Data: <searchLink fieldCode="JN" term="%228503886%22">Journal of hepatology</searchLink> [J Hepatol] 2025 Jul; Vol. 83 (1), pp. 81-91. <i>Date of Electronic Publication: </i>2025 Jan 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8503886 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1600-0641 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201688278%22">01688278 </searchLink><i>NLM ISO Abbreviation: </i>J Hepatol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jhep.2024.12.047
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      – Code: eng
        Text: English
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              Text: 2025 Jul
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