Oral obeldesivir provides postexposure protection against Marburg virus in nonhuman primates.

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Title: Oral obeldesivir provides postexposure protection against Marburg virus in nonhuman primates.
Authors: Cross RW; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Woolsey C; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Prasad AN; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Borisevich V; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Agans KN; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Deer DJ; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Harrison MB; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Dobias NS; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Fenton KA; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Cihlar T; Gilead Sciences, Inc., Foster City, CA, USA., Nguyen AQ; Gilead Sciences, Inc., Foster City, CA, USA., Babusis D; Gilead Sciences, Inc., Foster City, CA, USA., Bannister R; Gilead Sciences, Inc., Foster City, CA, USA., Vermillion MS; Gilead Sciences, Inc., Foster City, CA, USA., Chu VC; Gilead Sciences, Inc., Foster City, CA, USA., Geisbert TW; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA. twgeisbe@utmb.edu.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA. twgeisbe@utmb.edu.
Source: Nature medicine [Nat Med] 2025 Apr; Vol. 31 (4), pp. 1303-1311. Date of Electronic Publication: 2025 Jan 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-170X
DOI:10.1038/s41591-025-03496-y