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Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology development.

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Title: Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology development.
Authors: Friedland BA; Center for Biomedical Research, Population Council, New York, NY, United States of America., Gundacker H; Statistical Center for HIV/AIDS Research and Prevention (SCHARP), Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Achilles SL; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America., Chen BA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America., Hoesley C; University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, United States of America., Richardson BA; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Biostatistics and Global Health, University of Washington, Seattle, Washington, United States of America., Kelly CW; Statistical Center for HIV/AIDS Research and Prevention (SCHARP), Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Piper J; National Institutes of Allergy and Infectious Disease, NIH, Bethesda, Maryland, United States of America., Johnson S; FHI 360, Durham, North Carolina, United States of America., Devlin B; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Steytler J; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Kleinbeck K; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Dangi B; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Friend C; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Song M; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America., Mensch B; Population Council, New York, NY, United States of America., van der Straten A; RTI International, San Francisco, CA, United States of America., Jacobson C; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Hendrix CW; Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Brown J; Contraceptive Development Program, DIPHR, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, United States of America., Blithe D; Contraceptive Development Program, DIPHR, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, United States of America., Hiller SL; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America.
Corporate Authors: MTN-030/IPM 041 and MTN-044/IPM 053/CCN019 Protocol Teams for the Microbicide Trials Network and the Contraceptive Clinical Trials Network
Source: PloS one [PLoS One] 2025 Jan 14; Vol. 20 (1), pp. e0312957. Date of Electronic Publication: 2025 Jan 14 (Print Publication: 2025).
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology development.
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  Data: <searchLink fieldCode="AU" term="%22Friedland+BA%22">Friedland BA</searchLink>; Center for Biomedical Research, Population Council, New York, NY, United States of America.<br /><searchLink fieldCode="AU" term="%22Gundacker+H%22">Gundacker H</searchLink>; Statistical Center for HIV/AIDS Research and Prevention (SCHARP), Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Achilles+SL%22">Achilles SL</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Chen+BA%22">Chen BA</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Hoesley+C%22">Hoesley C</searchLink>; University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, United States of America.<br /><searchLink fieldCode="AU" term="%22Richardson+BA%22">Richardson BA</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Biostatistics and Global Health, University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Kelly+CW%22">Kelly CW</searchLink>; Statistical Center for HIV/AIDS Research and Prevention (SCHARP), Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Piper+J%22">Piper J</searchLink>; National Institutes of Allergy and Infectious Disease, NIH, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Johnson+S%22">Johnson S</searchLink>; FHI 360, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Devlin+B%22">Devlin B</searchLink>; International Partnership for Microbicides, Silver Spring, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Steytler+J%22">Steytler J</searchLink>; International Partnership for Microbicides, Silver Spring, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Kleinbeck+K%22">Kleinbeck K</searchLink>; International Partnership for Microbicides, Silver Spring, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Dangi+B%22">Dangi B</searchLink>; International Partnership for Microbicides, Silver Spring, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Friend+C%22">Friend C</searchLink>; International Partnership for Microbicides, Silver Spring, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Song+M%22">Song M</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Mensch+B%22">Mensch B</searchLink>; Population Council, New York, NY, United States of America.<br /><searchLink fieldCode="AU" term="%22van+der+Straten+A%22">van der Straten A</searchLink>; RTI International, San Francisco, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Jacobson+C%22">Jacobson C</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Hendrix+CW%22">Hendrix CW</searchLink>; Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Brown+J%22">Brown J</searchLink>; Contraceptive Development Program, DIPHR, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Blithe+D%22">Blithe D</searchLink>; Contraceptive Development Program, DIPHR, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Hiller+SL%22">Hiller SL</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2025 Jan 14; Vol. 20 (1), pp. e0312957. <i>Date of Electronic Publication: </i>2025 Jan 14 (<i>Print Publication: </i>2025).
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