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Hypomorphic RAG2 Deficiency Promotes Selection of Self-Reactive B Cells.

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Title: Hypomorphic RAG2 Deficiency Promotes Selection of Self-Reactive B Cells.
Authors: Thouvenel CD; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA., Tipton CM; Lowance Center for Human Immunology, Emory University School of Medicine, Atlanta, GA, USA., Yamazaki Y; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Zhang TT; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA., Rylaarsdam S; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA., Hom JR; Lowance Center for Human Immunology, Emory University School of Medicine, Atlanta, GA, USA., Snead C; Immunome Inc, Bothell, WA, USA., Zhu C; Department of Immunology, Microarray and Immune Phenotyping Core, University of Texas Southwestern Medical Center, Dallas, TX, USA., Li QZ; Genecopia Inc, Rockville, MD, USA., Lee YN; Pediatric Department A and the Immunology Service, Ramat-Gan and Sackler Faculty of Medicine, 'Edmond and Lily Safra' Children's Hospital, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer, Tel-Aviv University, Tel-Aviv, Israel., Kawai T; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Haque N; Bioinformatics Research and Development Laboratory, Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, USA., Zimmermann MT; Bioinformatics Research and Development Laboratory, Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, USA., Ponnan SM; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA., Jackson SW; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.; Department of Pediatrics, University of Washington, Seattle, WA, USA., James RG; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA., Sanz I; Lowance Center for Human Immunology, Emory University School of Medicine, Atlanta, GA, USA., Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Torgerson TR; Allen Institute for Immunology, Seattle, WA, USA., Ochs HD; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.; Department of Pediatrics, University of Washington, Seattle, WA, USA., Rawlings DJ; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA. drawlings@uw.edu.; Department of Pediatrics, University of Washington, Seattle, WA, USA. drawlings@uw.edu.; Department of Immunology, University of Washington, Seattle, WA, USA. drawlings@uw.edu., Allenspach EJ; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA. eric.allenspach@seattlechildrens.org.; Department of Pediatrics, University of Washington, Seattle, WA, USA. eric.allenspach@seattlechildrens.org.
Source: Journal of clinical immunology [J Clin Immunol] 2025 Jan 15; Vol. 45 (1), pp. 66. Date of Electronic Publication: 2025 Jan 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 8102137 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2592 (Electronic) Linking ISSN: 02719142 NLM ISO Abbreviation: J Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hypomorphic RAG2 Deficiency Promotes Selection of Self-Reactive B Cells.
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  Data: <searchLink fieldCode="AU" term="%22Thouvenel+CD%22">Thouvenel CD</searchLink>; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Tipton+CM%22">Tipton CM</searchLink>; Lowance Center for Human Immunology, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Yamazaki+Y%22">Yamazaki Y</searchLink>; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+TT%22">Zhang TT</searchLink>; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Rylaarsdam+S%22">Rylaarsdam S</searchLink>; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Hom+JR%22">Hom JR</searchLink>; Lowance Center for Human Immunology, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Snead+C%22">Snead C</searchLink>; Immunome Inc, Bothell, WA, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+C%22">Zhu C</searchLink>; Department of Immunology, Microarray and Immune Phenotyping Core, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Li+QZ%22">Li QZ</searchLink>; Genecopia Inc, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lee+YN%22">Lee YN</searchLink>; Pediatric Department A and the Immunology Service, Ramat-Gan and Sackler Faculty of Medicine, 'Edmond and Lily Safra' Children's Hospital, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer, Tel-Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Kawai+T%22">Kawai T</searchLink>; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Haque+N%22">Haque N</searchLink>; Bioinformatics Research and Development Laboratory, Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.<br /><searchLink fieldCode="AU" term="%22Zimmermann+MT%22">Zimmermann MT</searchLink>; Bioinformatics Research and Development Laboratory, Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.<br /><searchLink fieldCode="AU" term="%22Ponnan+SM%22">Ponnan SM</searchLink>; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Jackson+SW%22">Jackson SW</searchLink>; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.; Department of Pediatrics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22James+RG%22">James RG</searchLink>; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Sanz+I%22">Sanz I</searchLink>; Lowance Center for Human Immunology, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Notarangelo+LD%22">Notarangelo LD</searchLink>; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Torgerson+TR%22">Torgerson TR</searchLink>; Allen Institute for Immunology, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ochs+HD%22">Ochs HD</searchLink>; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.; Department of Pediatrics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Rawlings+DJ%22">Rawlings DJ</searchLink>; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA. drawlings@uw.edu.; Department of Pediatrics, University of Washington, Seattle, WA, USA. drawlings@uw.edu.; Department of Immunology, University of Washington, Seattle, WA, USA. drawlings@uw.edu.<br /><searchLink fieldCode="AU" term="%22Allenspach+EJ%22">Allenspach EJ</searchLink>; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA. eric.allenspach@seattlechildrens.org.; Department of Pediatrics, University of Washington, Seattle, WA, USA. eric.allenspach@seattlechildrens.org.
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  Data: <searchLink fieldCode="JN" term="%228102137%22">Journal of clinical immunology</searchLink> [J Clin Immunol] 2025 Jan 15; Vol. 45 (1), pp. 66. <i>Date of Electronic Publication: </i>2025 Jan 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8102137 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-2592 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202719142%22">02719142 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Immunol <i>Subsets: </i>MEDLINE
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