Prolonged persistence of mutagenic DNA lesions in somatic cells.

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Bibliographic Details
Title: Prolonged persistence of mutagenic DNA lesions in somatic cells.
Authors: Spencer Chapman M; Wellcome Sanger Institute, Hinxton, UK.; Department of Haemato-oncology, Barts Cancer Institute, London, UK., Mitchell E; Wellcome Sanger Institute, Hinxton, UK.; Cambridge Stem Cell Institute, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Yoshida K; Wellcome Sanger Institute, Hinxton, UK., Williams N; Wellcome Sanger Institute, Hinxton, UK., Fabre MA; Wellcome Sanger Institute, Hinxton, UK.; Cambridge Stem Cell Institute, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Ranzoni AM; Wellcome Sanger Institute, Hinxton, UK., Robinson PS; Wellcome Sanger Institute, Hinxton, UK., Kregar LD; Wellcome Sanger Institute, Hinxton, UK., Wilk M; Department of Medical Oncology and Hematology, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Boettcher S; Department of Medical Oncology and Hematology, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Mahbubani K; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge Biorepository for Translational Medicine, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK., Saeb Parsy K; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge Biorepository for Translational Medicine, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK., Gowers KHC; Lungs For Living Research Centre, UCL Respiratory, University College London, London, UK., Janes SM; Lungs For Living Research Centre, UCL Respiratory, University College London, London, UK., Ng SWK; Wellcome Sanger Institute, Hinxton, UK., Hoare M; Early Cancer Institute, University of Cambridge, Cambridge, UK., Green AR; Cambridge Stem Cell Institute, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Vassiliou GS; Wellcome Sanger Institute, Hinxton, UK.; Cambridge Stem Cell Institute, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Cvejic A; Wellcome Sanger Institute, Hinxton, UK.; Cambridge Stem Cell Institute, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark., Manz MG; Department of Medical Oncology and Hematology, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Laurenti E; Cambridge Stem Cell Institute, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Martincorena I; Wellcome Sanger Institute, Hinxton, UK., Stratton MR; Wellcome Sanger Institute, Hinxton, UK., Nangalia J; Wellcome Sanger Institute, Hinxton, UK.; Cambridge Stem Cell Institute, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Coorens THH; Wellcome Sanger Institute, Hinxton, UK.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Campbell PJ; Wellcome Sanger Institute, Hinxton, UK. pc8@sanger.ac.uk.; Cambridge Stem Cell Institute, Cambridge, UK. pc8@sanger.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK. pc8@sanger.ac.uk.
Source: Nature [Nature] 2025 Feb; Vol. 638 (8051), pp. 729-738. Date of Electronic Publication: 2025 Jan 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-024-08423-8